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对于无法挽救的感染性全膝关节置换术,镀银关节融合植入物能否成为膝上截肢的可行替代方案?

Can a Silver-Coated Arthrodesis Implant Provide a Viable Alternative to Above Knee Amputation in the Unsalvageable, Infected Total Knee Arthroplasty?

作者信息

Wilding Chris P, Cooper George A, Freeman Alexandra K, Parry Michael C, Jeys Lee

机构信息

Royal Orthopaedic Hospital, Birmingham, West Midlands, United Kingdom.

出版信息

J Arthroplasty. 2016 Nov;31(11):2542-2547. doi: 10.1016/j.arth.2016.04.009. Epub 2016 Apr 22.

Abstract

BACKGROUND

In the unsalvageable, infected total knee arthroplasty, knee arthrodesis is one treatment option with lower reported reinfection rates compared with repeated 2-stage revision and improved function compared with amputation. One possible method for reducing incidence of recurrent infection treated by arthrodesis is the use of a silver-coated implant. We report our experience of silver-coated arthrodesis nails used for managing infected revision arthroplasty. We primarily assess the rate of reinfection and rate of amputation and report functional outcome measures.

METHODS

Retrospective analysis of all patients undergoing knee arthrodesis with a silver-coated arthrodesis nail between 2008 and 2014. Patient-reported data were recorded prearthrodesis and postarthrodesis (Oxford Knee Score and Short Form-36) as well as evidence of recurrent of infection, subsequent surgery, and the necessity for amputation.

RESULTS

Eight patients underwent arthrodesis using the silver-coated arthrodesis nail. Mean duration of follow-up was 16 months (5-35 months). At the point of follow-up, there were no amputations, deaths, or implant revisions. One case of recurrent infection was successfully treated with washout and debridement. The mean prearthrodesis and postarthrodesis Oxford Knee Score difference was +8.9 points (P = .086) with significantly improved pain (P = .019), night pain (P = .021), and ease of standing (P = .003).

CONCLUSION

Arthrodesis of the knee using a silver-coated intramedullary device is successful in eradicating infection and allowing limb conservation. Where infection does recur, this can be successfully treated with implant retention. The use of a silver-coated arthrodesis nail should be considered as an alternative to amputation for patients with a multiply revised and infected total knee arthroplasty.

摘要

背景

在无法挽救的感染性全膝关节置换术中,膝关节融合术是一种治疗选择,与重复的两阶段翻修术相比,其报告的再感染率较低,与截肢相比,功能有所改善。减少膝关节融合术治疗复发性感染发生率的一种可能方法是使用银涂层植入物。我们报告了使用银涂层融合钉治疗感染性翻修关节成形术的经验。我们主要评估再感染率和截肢率,并报告功能结局指标。

方法

对2008年至2014年间所有使用银涂层融合钉进行膝关节融合术的患者进行回顾性分析。记录患者术前和术后报告的数据(牛津膝关节评分和简短健康调查问卷-36)以及再感染、后续手术和截肢必要性的证据。

结果

8例患者使用银涂层融合钉进行了关节融合术。平均随访时间为16个月(5 - 35个月)。在随访时,没有截肢、死亡或植入物翻修情况。1例复发性感染经冲洗和清创成功治疗。术前和术后牛津膝关节评分的平均差异为+8.9分(P = .086),疼痛(P = .019)、夜间疼痛(P = .021)和站立 ease(P = .003)有显著改善。

结论

使用银涂层髓内装置进行膝关节融合术成功根除了感染并保留了肢体。如果感染确实复发,可以通过保留植入物成功治疗。对于多次翻修且感染的全膝关节置换术患者,应考虑使用银涂层融合钉作为截肢的替代方法。

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