Kesavadev J, Rasheed S A
Jothydev's Diabetes and Research Center, Kerala.
J Assoc Physicians India. 2006 Dec;54:951-2.
Gatifloxacin, a commonly prescribed antimicrobial can produce profound hypoglycemia and disturbances in glucose homeostasis especially in diabetes patients on sulphonylureas. Also new onset disturbances in glucose homeostasis can occur in patients who were unaffected by the previous use of gatifloxacin. Therefore it is suggested that gatifloxacin is better avoided in patients with diabetes and in the elderly.
加替沙星是一种常用的抗菌药物,可导致严重低血糖及葡萄糖稳态紊乱,尤其是在服用磺脲类药物的糖尿病患者中。此外,既往使用加替沙星未受影响的患者也可能出现新的葡萄糖稳态紊乱。因此,建议糖尿病患者及老年人避免使用加替沙星。