Erden I Aydin, Artukoglu Feyzi, Gozacan Ahmet, Ozgen Saadet
Department of Anesthesiology and Reanimation, Faculty of Medicine, Hacettepe University, Sihhiye 06100, Ankara, Turkey.
Saudi Med J. 2007 Mar;28(3):364-8.
Extracorporeal Shockwave Lithotripsy (ESWL) is an effective and safe way for treatment of upper urinary system stones. For pediatric patients, throughout ESWL, sufficient sedation and analgesia is needed to cope with the procedural pain. In this study, our goal was to compare 2 methods of intravenous anesthesia, applied to pediatric patients during ESWL.
Forty patients, between 3 months and 15 years of age who were admitted to the Faculty of Medicine, Hacettepe University, Turkey between September 2003 to September 2004 with upper urinary system calculi were randomized into 2 groups. All patients received intranasal midazolam 0.3 mg/kg premedication. Group K received intravenous (iv) ketamine 2 mg/kg; Group PF received a bolus of iv propofol 3 mg/kg and iv fentanyl 1 microg/kg along with a propofol infusion of 1 mg/kg/hr throughout the procedure. Procedural, recovery and discharge times, incidences of intra and post-procedural complications were compared.
Demographics, procedural and discharge times were similar in 2 groups. While recovery times and post-procedural complication incidence was higher for the Group K, intra-procedural complication incidence was higher for the Group PF.
Although both protocols do not differ much according to ease of application and efficacy in providing sufficient analgesia for ESWL, they have their corresponding side effects and they can only be practiced safely by experienced anesthesiologists in a monitorized and well equipped setting.
体外冲击波碎石术(ESWL)是治疗上尿路结石的一种有效且安全的方法。对于儿科患者,在整个ESWL过程中,需要足够的镇静和镇痛来应对操作过程中的疼痛。在本研究中,我们的目标是比较两种在ESWL期间应用于儿科患者的静脉麻醉方法。
2003年9月至2004年9月间,土耳其哈杰泰佩大学医学院收治的40例年龄在3个月至15岁之间的上尿路结石患儿被随机分为两组。所有患者术前均接受0.3 mg/kg的鼻内咪达唑仑预处理。K组静脉注射2 mg/kg氯胺酮;PF组在整个手术过程中静脉注射3 mg/kg丙泊酚和1 μg/kg芬太尼推注,并以1 mg/kg/小时的速度输注丙泊酚。比较两组的手术时间、恢复时间、出院时间以及术中及术后并发症的发生率。
两组的人口统计学数据、手术时间和出院时间相似。K组的恢复时间和术后并发症发生率较高,而PF组的术中并发症发生率较高。
虽然两种方案在应用的难易程度和为ESWL提供足够镇痛的效果方面差异不大,但它们都有相应的副作用,并且只能由经验丰富的麻醉医生在有监测设备且装备完善的环境中安全实施。