Kang Seok-Ho, Kim Myung-Joon, Park Min-Gu, Park Hong-Seok, Moon Du-Geon, Sung Deuk-Jae, Kim Hyun-Chul, Chae Yang-Seok, Cheon Jun, Kim Je-Jong
Department of Urology, Korea University Hospital, Seoul 136-705, Korea.
Asian J Androl. 2007 Mar;9(2):275-9. doi: 10.1111/j.1745-7262.2007.00235.x.
We describe an unusual case of extragastrointestinal stromal tumor (EGIST) presenting as a scrotal mass. A 71-year-old man presented with a gradually enlarging scrotal mass with a 20-year duration. Physical examination revealed a huge (as large as volleyball), round, nontender mass occupying the whole scrotum, which was resected completely. Clinical and radiological findings did not comply with any other primary site disease. Under histological examination, the tumor showed a spindle cell pattern with low cellularity, absence of necrotic and mitotic features. immunohistochemical analysis revealed the tumor reactive for CD117 and CD34, while negative for smooth muscle actin, desmin and S-100 protein. To our knowledge, this is the first reported case of an EGIST involving the scrotum.
我们描述了一例表现为阴囊肿块的胃肠道外间质瘤（EGIST）罕见病例。一名71岁男性患者，阴囊肿块逐渐增大已持续20年。体格检查发现一个巨大（如排球大小）、圆形、无压痛的肿块占据整个阴囊，该肿块被完整切除。临床和影像学检查结果不符合任何其他原发部位疾病。组织学检查显示肿瘤呈梭形细胞形态，细胞密度低，无坏死和有丝分裂特征。免疫组化分析显示肿瘤对CD117和CD34呈阳性反应，而对平滑肌肌动蛋白、结蛋白和S-100蛋白呈阴性反应。据我们所知，这是首例报道的累及阴囊的EGIST病例。
