Ryvlin P, Garcia-Larrea L, Philippon B, Froment J C, Fischer C, Revol M, Mauguière F
EEG Department, Neurological Hospital, Lyon, France.
Epilepsia. 1992 Jan-Feb;33(1):28-35. doi: 10.1111/j.1528-1157.1992.tb02279.x.
Single-photon emission computed tomography (SPECT) and [99mTc]HMPAO were used to assess the functional significance of nonspecific magnetic resonance imaging (MRI) abnormalities observed in patients with temporal lobe epilepsy and no focal lesion on CT scan. We studied 18 patients whose MRI was normal or showed high signal intensity on T2-weighted images (T2WIs) at the site of the EEG focus in 11 and 7 cases, respectively. EEG was monitored during regional cerebral blood flow (rCBF) study. Lateralized hypoperfusion was present in 7 of 17 interictal (41%) and in one postictal cases; it was located in the temporal lobe on the side of the EEG focus in all, and was significantly more frequent in patients with high signal intensity on T2WI (86%) than in patients with a normal MRI (18%). The degree of temporal perfusion asymmetry measured in each individual was higher in patients whose MRI was abnormal.
单光子发射计算机断层扫描（SPECT）和[99mTc]六甲基丙烯胺肟（HMPAO）被用于评估颞叶癫痫患者中观察到的非特异性磁共振成像（MRI）异常的功能意义，这些患者在CT扫描上没有局灶性病变。我们研究了18例患者，其中11例和7例患者的MRI分别正常或在脑电图（EEG）病灶部位的T2加权图像（T2WI）上显示高信号强度。在局部脑血流（rCBF）研究期间监测EEG。17例发作间期患者中有7例（41%）和1例发作后期患者存在侧化灌注不足；所有患者的灌注不足均位于EEG病灶一侧的颞叶，且T2WI上高信号强度患者（86%）的灌注不足明显比MRI正常患者（18%）更常见。MRI异常患者中，个体测量的颞叶灌注不对称程度更高。
