Harmouche H, Maamar M, Sahnoune I, Tazi-Mezalek Z, Aouni M, Maaouni A
Department of Internal Medicine Hospital Ibn Sina Rabat, Morocco.
Eur J Intern Med. 2007 Mar;18(2):146-7. doi: 10.1016/j.ejim.2006.09.009.
Behçet's disease (BD) is an uncommon cause of fever of unknown origin. We report two cases, both involving 42-year-old males, who initially presented with prolonged fever and who were ultimately diagnosed as having BD after a delay of 12 and 21 months, respectively. Both patients developed pulmonary aneurysms. Although fevers resolved after therapy, both patients died within the first year after diagnosis. Clinicians should be aware that long-term fever may be an inaugural sign of BD, especially in individuals living in countries along the ancient Silk Road or Mediterranean basin.
白塞病（BD）是不明原因发热的罕见病因。我们报告两例病例，均为42岁男性，最初均表现为长期发热，分别在延误12个月和21个月后最终被诊断为白塞病。两名患者均出现了肺动脉瘤。尽管治疗后发热消退，但两名患者均在诊断后的第一年内死亡。临床医生应意识到长期发热可能是白塞病的首发症状，尤其是在居住在古代丝绸之路沿线国家或地中海盆地的人群中。
