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鼻咽血管纤维瘤局部麻醉后癫痫发作。

Seizure after local anesthesia for nasopharyngeal angiofibroma.

作者信息

Tsai Cheng-Jing, Wang Hsun-Mo, Lu I-Chen, Tai Chih-Feng, Wang Ling-Feng, Soo Lee-Ying, Lu David Vi

机构信息

Department of Anesthesiology, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.

出版信息

Kaohsiung J Med Sci. 2007 Feb;23(2):97-100. doi: 10.1016/S1607-551X(09)70383-3.

DOI:10.1016/S1607-551X(09)70383-3
PMID:17339174
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11918217/
Abstract

We report a young male patient who experienced seizure after local injection of 3 mL 2% lidocaine with epinephrine 1:200,000 around a recurrent nasal angiofibroma. After receiving 100% oxygen via mask and thiamylal sodium, the patient had no residual neurologic sequelae. Seizure immediately following the injection of local anesthetics in the nasal cavity is probably due to injection into venous or arterial circulation with retrograde flow to the brain circulation. Further imaging study or angiography should be done before head and neck surgeries, especially in such highly vascular neoplasm.

摘要

我们报告了一名年轻男性患者,其在复发性鼻血管纤维瘤周围局部注射3毫升含1:200,000肾上腺素的2%利多卡因后出现癫痫发作。经面罩给予100%氧气并注射硫喷妥钠后,患者未遗留神经后遗症。鼻腔局部麻醉药注射后立即发生癫痫发作可能是由于药物注入静脉或动脉循环并逆行流入脑循环所致。在头颈部手术前,尤其是在处理这种高血管性肿瘤时,应进行进一步的影像学检查或血管造影。

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Seizure after local anesthesia for nasopharyngeal angiofibroma.鼻咽血管纤维瘤局部麻醉后癫痫发作。
Kaohsiung J Med Sci. 2007 Feb;23(2):97-100. doi: 10.1016/S1607-551X(09)70383-3.
2
[Endoscopic nasal surgery in treatment of nasopharyngeal angiofibroma].[内镜下鼻腔手术治疗鼻咽血管纤维瘤]
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本文引用的文献

1
Apnea and seizures following retrobulbar local anesthetic injection.球后局部麻醉注射后出现呼吸暂停和癫痫发作。
J Clin Anesth. 2003 Jun;15(4):267-70. doi: 10.1016/s0952-8180(03)00025-4.
2
Juvenile angiofibroma: case report and the role of endoscopic resection.青少年血管纤维瘤:病例报告及内镜下切除术的作用
Singapore Med J. 2002 Apr;43(4):208-10.
3
Local anaesthesia outside the operating room.
Hong Kong Med J. 2002 Apr;8(2):106-13.
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Endoscopic treatment of juvenile nasopharyngeal angiofibroma.
Am J Rhinol. 1999 May-Jun;13(3):213-9. doi: 10.2500/105065899781389812.
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The incidence of complications associated with local anesthesia in dentistry.牙科局部麻醉相关并发症的发生率。
Anesth Prog. 1997 Fall;44(4):132-41.
6
Intravascular lidocaine toxicity: influence of epinephrine and route of administration.血管内利多卡因毒性:肾上腺素及给药途径的影响
Anesth Prog. 1985 Mar-Apr;32(2):57-61.
7
Adverse effects of local anaesthetics.局部麻醉药的不良反应。
Br J Anaesth. 1987 Jan;59(1):78-95. doi: 10.1093/bja/59.1.78.
8
Juvenile nasopharyngeal angiofibroma.
Otolaryngol Clin North Am. 1986 Nov;19(4):647-57.