脆性X综合征或特纳综合征女性的觉醒调节
Arousal modulation in females with fragile X or Turner syndrome.
作者信息
Roberts Jane, Mazzocco Michèle M M, Murphy Melissa M, Hoehn-Saric Rudolf
机构信息
Frank Porter Graham Child Development Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
出版信息
J Autism Dev Disord. 2008 Jan;38(1):20-7. doi: 10.1007/s10803-007-0356-6. Epub 2007 Mar 6.
Abstract
The present study was carried out to examine physiological arousal modulation (heart activity and skin conductance, across baseline and cognitive tasks, in females with fragile X or Turner syndrome and a comparison group of females with neither syndrome. Relative to the comparison group, for whom a greater increase in skin conductance was associated with poor arithmetic performance and less risk taking behavior, females with fragile X displayed a minimal increase in heart activity that was nevertheless associated with poor performance on mental arithmetic. In contrast, no arousal-cognitive performance relationship emerged for the group with Turner syndrome. Taken together, our findings suggest that distinct profiles of arousal modulation might be associated with cognitive deficits in these syndrome populations.
摘要
本研究旨在考察脆性X综合征或特纳综合征女性以及非综合征女性对照组在基线和认知任务期间的生理唤醒调节（心脏活动和皮肤电传导）情况。相对于对照组，皮肤电传导增加幅度越大与算术表现较差及冒险行为较少相关，脆性X综合征女性的心脏活动仅有极小幅度增加，但这仍与心算表现较差相关。相比之下，特纳综合征组未出现唤醒与认知表现的关系。综合来看，我们的研究结果表明，这些综合征人群中不同的唤醒调节特征可能与认知缺陷相关。
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