Pravettoni D, Doll K, Hummel M, Cavallone E, Morandi N, Belloli A G
Ospedale Veterinario Grandi Animali, Clinica dei Ruminanti e del Suino, Università degli Studi di Milano, Italy.
Dtsch Tierarztl Wochenschr. 2007 Feb;114(2):58-63.
The objective of the study was to analyze glucose metabolism and abomasal myoelectrical activity during an intravenous glucose tolerance test in cows operated for LDA. Three dairy cows, at the onset of lactation, suffering from left displaced abomasum were selected from the animals presented at the clinic. During surgical therapy, one pair of electrodes was placed in the smooth muscle of the abomasal body, the pars pylorica and the duodenum respectively. The animals were subjected to electromyography on five occasions during hospital admittance (Days 1, 2, 3, 5 and 7 post-operative); their insulin, glucagon, glucose, beta-hydroxybutyrate and NEFA levels were then measured. Two days after surgery, the animals were subjected to an intravenous glucose load (300 g glucose in 30 min) during abomaso-duodenal electromyography. The findings indicate that the three animals had glucose metabolism disorders during hospitalization. The abomaso-duodenal myoelectric activity of Cows 1 and 3 was lower than in Cow 2. During the glucose load, the analysis of hormones and metabolites showed that there were different degrees of reactivity and that myoelectric activity differed in the 3 cows. The results of the study suggest that despite the surgical reposition of the abomasum, disorders of abomasal motility persist in different degrees in cows operated for LDA and could be influenced by glucose administrations.
本研究的目的是分析接受左方变位皱胃手术的奶牛在静脉注射葡萄糖耐量试验期间的葡萄糖代谢和皱胃肌电活动。从诊所就诊的动物中挑选出三头处于泌乳初期、患有左方变位皱胃的奶牛。在手术治疗期间,分别在皱胃体、幽门部和十二指肠的平滑肌中放置一对电极。在住院期间(术后第1、2、3、5和7天)对动物进行五次肌电图检查;然后测量它们的胰岛素、胰高血糖素、葡萄糖、β-羟基丁酸和非酯化脂肪酸水平。手术后两天,在皱胃-十二指肠肌电图检查期间,给动物静脉注射葡萄糖负荷(30分钟内注射300克葡萄糖)。研究结果表明,这三头动物在住院期间存在葡萄糖代谢紊乱。奶牛1和3的皱胃-十二指肠肌电活动低于奶牛2。在葡萄糖负荷期间,对激素和代谢物的分析表明,三头奶牛有不同程度的反应性,肌电活动也有所不同。研究结果表明,尽管对皱胃进行了手术复位,但接受左方变位皱胃手术的奶牛仍存在不同程度的皱胃运动紊乱,且可能受葡萄糖给药的影响。