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[2001 - 2003年在哥伦比亚麦德林控制糖尿病及其并发症]

[Controlling diabetes mellitus and its complications in Medellín, Colombia, 2001-2003].

作者信息

Villegas Perrasse Alberto, Abad Sol Beatriz, Faciolince Santiago, Hernández Nayeli, Maya Camilo, Parra Lucrecia, Rivas Edison, Vallejo Pilar

机构信息

Servicio de Endocrinología, Hospital Universitario San Vicente de Paul, Universidad de Antioquia, Antioquia, Colombia.

出版信息

Rev Panam Salud Publica. 2006 Dec;20(6):393-402. doi: 10.1590/s1020-49892006001100005.

Abstract

OBJECTIVES

To identify the principal sociodemographic, clinical, and behavioral characteristics of patients participating in diabetic care programs in the city of Medellín, Colombia, and to evaluate progress toward the goal of metabolic control and diabetic care standards.

METHODS

A cross-sectional, descriptive study was done, analyzing the clinical records of patients who had been participating for at least 6 months in the diabetic care programs of nine health care centers in Medellín. The study period ran from January 2001 to December 2003. The following data were collected: sociodemographic (age and sex), clinical (time since disease onset, diabetes type and treatment, and concurrent illnesses and their treatment), lifestyle habits (exercise routine, smoking, and sugar and fat consumption), chronic complications, and laboratory test results from the prior year. Questionable or missing data were categorized as unavailable.

RESULTS

Of the 3 583 clinical histories evaluated, we were able to confirm the form of diabetes for 3 554 patients. Of those 3 554, 95.1% had type 2 diabetes. Overall, 56.9% (95% confidence interval (95% CI): 55.2% to 58.6%) of the patients exercised regularly, 15.1% (95% CI: 13.9% to 16.3%) were current smokers, 17.7% (95% CI: 16.4% to 19.0%) were former smokers, and 67.2% (95% CI: 65.6% to 68.8%) had never smoked. In all, 21.0% (95% CI: 19.6% to 22.5%) of the patients consumed sugar regularly, while 24.8% (95% CI: 23.3% to 26.3%) consumed fats and only 19.5% (95% CI: 17.8% to 21.3%) were self-monitoring their glucose levels at least weekly. Among the type 2 diabetics, 68.8% had high blood pressure, and 98.2% had dyslipidemia. The average body mass index was 28.0 kg/m(2) (95% CI: 27.8 to 28.2). The average number of medications that the patients were taking to treat type 2 diabetes was 1.3; to treat high blood pressure, 1.9; and to treat dyslipidemia, 0.6. There were no data on low-density lipoprotein (LDL) cholesterol in 44.8% of the clinical records, and no data on high-density lipoprotein (HDL) cholesterol in 16.4% of the records. Among the complications, the most common were ocular ones (31.8%; 95% CI: 30.1% to 33.5%), followed by renal ones (25.9%; 95% CI: 24.4% to 27.5%), and cardiovascular ones (22.5%; 95% CI: 21.1% to 23.8%). Cholesterol control achievement was inadequate for LDL (reached by only 14.2% of the patients), for triglycerides (36.9% of patients), and HDL (47.4% of patients).

CONCLUSIONS

Among the study population in Medellín, the three chronic complications with the greatest impact on prognosis and health care costs of the diabetics were nephropathy, retinopathy, and dyslipidemia. The noticeable amount of unavailable data in the clinical records could be greatly reduced by standardizing the clinical record forms and by periodic quality checks of the records themselves.

摘要

目的

确定参与哥伦比亚麦德林市糖尿病护理项目患者的主要社会人口统计学、临床和行为特征,并评估代谢控制目标和糖尿病护理标准的进展情况。

方法

开展了一项横断面描述性研究,分析了在麦德林市9个医疗中心的糖尿病护理项目中参与至少6个月的患者的临床记录。研究时间段为2001年1月至2003年12月。收集了以下数据:社会人口统计学数据(年龄和性别)、临床数据(疾病发病时间、糖尿病类型及治疗、并发疾病及其治疗)、生活习惯(锻炼习惯、吸烟情况以及糖和脂肪摄入)、慢性并发症以及上一年的实验室检查结果。可疑或缺失的数据归类为不可用数据。

结果

在评估的3583份临床病历中,我们能够确定3554例患者的糖尿病类型。在这3554例患者中,95.1%患有2型糖尿病。总体而言,56.9%(95%置信区间(95%CI):55.2%至58.6%)的患者定期锻炼,15.1%(95%CI:13.9%至16.3%)的患者目前吸烟,17.7%(95%CI:16.4%至19.0%)的患者既往吸烟,67.2%(95%CI:65.6%至68.8%)的患者从不吸烟。总计21.0%(95%CI:19.6%至22.5%)的患者经常食用糖,24.8%(95%CI:23.3%至26.3%)的患者食用脂肪,只有19.5%(95%CI:17.8%至21.3%)的患者至少每周自我监测血糖水平。在2型糖尿病患者中,68.8%患有高血压,98.2%患有血脂异常。平均体重指数为28.0kg/m²(95%CI:27.8至28.2)。患者治疗2型糖尿病平均服用药物数量为1.3种;治疗高血压为1.9种;治疗血脂异常为0.6种。44.8%的临床记录中没有低密度脂蛋白(LDL)胆固醇数据,16.4%的记录中没有高密度脂蛋白(HDL)胆固醇数据。在并发症中,最常见的是眼部并发症(31.8%;95%CI:30.1%至33.5%),其次是肾脏并发症(25.9%;95%CI:24.4%至27.5%)和心血管并发症(22.5%;95%CI:21.1%至23.8%)。LDL胆固醇控制达标率不足(仅14.2%的患者达标),甘油三酯控制达标率为36.9%,HDL胆固醇控制达标率为47.4%。

结论

在麦德林的研究人群中,对糖尿病患者预后和医疗费用影响最大的三种慢性并发症是肾病、视网膜病变和血脂异常。通过规范临床记录表格以及对记录本身进行定期质量检查,可大幅减少临床记录中大量不可用数据的情况。

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