Sperling R S, Joyner M, Hassett J, Kee R, Wheatley P, Bauer C
Department of Obstetrics/Gynecology, City Hospital Center at Elmhurst-Mount Sinai School of Medicine (CUNY), NY 10029.
Mt Sinai J Med. 1992 Jan;59(1):67-8.
Epidemic increases in active syphilis have been reported in the geographic areas hit hard by acquired immunodeficiency syndrome. Although both epidemics have been associated with illicit substance abuse, the extent to which recent increases in syphilis are linked to the human immunodeficiency virus (HIV-1) epidemic is uncertain. In order to define the frequency of syphilis and HIV-1 coinfection in the pregnant patients seen at City Hospital Center at Elmhurst, we saved syphilis-positive serologic specimens from obstetrical patients for anonymous HIV-1 antibody testing. Of 120 women who tested positive for syphilis, 7/120 (5.8%) had antibodies to HIV-1; of the 44 women with VDRL titers greater than or equal to 1:16 (suggestive of a recent infection), 1/44 (2.3%) had antibodies to HIV-1.
在受获得性免疫缺陷综合征重创的地理区域，已报告活动性梅毒的流行有所增加。尽管这两种流行病都与非法药物滥用有关，但近期梅毒增加与人类免疫缺陷病毒（HIV-1）流行的关联程度尚不确定。为了确定在埃尔姆赫斯特市医院中心就诊的孕妇中梅毒和HIV-1合并感染的频率，我们留存了产科患者梅毒阳性的血清学标本用于匿名HIV-1抗体检测。在120名梅毒检测呈阳性的女性中，7/120（5.8%）有HIV-1抗体；在44名VDRL滴度大于或等于1:16（提示近期感染）的女性中，1/44（2.3%）有HIV-1抗体。
