Milingos D, Doumplis D, Savage P, Seckl M, Lindsay I, Smith J R
West London Cancer Centre, Hammersmith Hospitals NHS Trust, London, United Kingdom.
Int J Gynecol Cancer. 2007 Jul-Aug;17(4):925-7. doi: 10.1111/j.1525-1438.2007.00881.x. Epub 2007 Mar 5.
Placental site trophoblastic tumors (PSTT) are the rarest form of gestational trophoblastic disease (GTD). The clinical management of PSTT differs from the other forms of GTD as surgery plays a more important role. The most common metastatic sites are the lung, liver, and vagina while spread to the adnexa is relatively unusual. We describe a case of a 35-year-old woman presenting with PSTT and ovarian metastasis who was successfully treated with radical hysterectomy, bilateral oophorectomy, pelvic lymph node dissection, and postoperative chemotherapy. The case highlights the possibility of ovarian metastases despite normal preoperative imaging and confirms the value of multidisciplinary management of this rare illness.
胎盘部位滋养细胞肿瘤(PSTT)是妊娠滋养细胞疾病(GTD)中最罕见的一种形式。PSTT的临床管理与其他形式的GTD不同,因为手术起着更重要的作用。最常见的转移部位是肺、肝和阴道,而转移至附件相对少见。我们描述了一例35岁患有PSTT并伴有卵巢转移的女性病例,该患者通过根治性子宫切除术、双侧卵巢切除术、盆腔淋巴结清扫术及术后化疗获得成功治疗。该病例凸显了尽管术前影像学检查正常但仍存在卵巢转移的可能性,并证实了对这种罕见疾病进行多学科管理的价值。