• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

《槐米对镰状细胞的逆转作用》。

The Reversion of Sickled Cells by Cajanus cajan.

机构信息

Department of Biochemistry, University of Port Harcourt, P.M.B. 5323 Port Harcourt, Nigeria.

出版信息

Planta Med. 1985 Dec;51(6):504-7. doi: 10.1055/s-2007-969576.

DOI:10.1055/s-2007-969576
PMID:17345271
Abstract

Boiled and crude ethanolic extracts of edible CAJANUS CAJAN beans were prepared and used for IN VITRO studies involving 14 individual blood samples obtained from confirmed sickle cell (HbSS) patients. It was demonstrated that the extracts were able not only to inhibit sickling in sodium metabisulphite solution, but also quickly reverted to normal morphology, already sickled erythrocytes. There was also a noticeable improvement in the general morphology of the sickle cell erythrocytes after coming into contact with the plant extracts.

摘要

食用腰果的水煮和粗提乙醇提取物被制备并用于涉及从确诊镰状细胞(HbSS)患者中获得的 14 份个体血液样本的体外研究。结果表明,这些提取物不仅能够抑制亚硫酸钠溶液中的镰状化,而且还能够迅速将已经镰状化的红细胞恢复正常形态。与植物提取物接触后,镰状细胞的一般形态也有明显改善。

相似文献

1
The Reversion of Sickled Cells by Cajanus cajan.《槐米对镰状细胞的逆转作用》。
Planta Med. 1985 Dec;51(6):504-7. doi: 10.1055/s-2007-969576.
2
Underutilized legumes, Cajanus cajan and Glycine max may bring about antisickling effect in sickle cell disease by modulation of redox homeostasis in sickled erythrocytes and alteration of its functional chemistry.未充分利用的豆类,如豇豆和大豆,可能通过调节镰状红细胞的氧化还原平衡和改变其功能化学性质,带来镰状细胞病的抗镰变效应。
J Food Biochem. 2022 Sep;46(9):e14322. doi: 10.1111/jfbc.14322. Epub 2022 Jul 27.
3
Evaluation of anti-sickling effects of two varieties of Cajanus cajan (L.) Huth on sickle cell beta thalassemia.评价两种木豆(Cajanus cajan(L.)Huth)对镰状细胞β地中海贫血的抗镰变作用。
J Ethnopharmacol. 2024 Sep 15;331:118280. doi: 10.1016/j.jep.2024.118280. Epub 2024 May 5.
4
The reversion of sickled cells by Cajanus cajan.
Planta Med. 1985 Dec(6):504-7.
5
The kinetics of reversal of pre-sickled erythrocytes by the aqueous extract of Cajanus cajan seeds.木豆种子水提取物对镰状前红细胞逆转的动力学
Phytother Res. 2002 Dec;16(8):748-50. doi: 10.1002/ptr.1026.
6
Sialic acid in sickle cell disease.镰状细胞病中的唾液酸
Clin Chem. 1988 Jul;34(7):1443-6.
7
Comparative study on the antiherpetic activity of aqueous and ethanolic extracts derived from Cajanus cajan (L.) Millsp.木豆水提取物和乙醇提取物抗疱疹活性的比较研究
Forsch Komplementmed. 2010 Mar;17(1):15-20. doi: 10.1159/000263619. Epub 2009 Jan 8.
8
Sickled erythrocytes, hyphema, and secondary glaucoma: IV. The rate and percentage of sickling of erythrocytes in rabbit aqueous humor, in vitro and in vivo.镰状红细胞、前房积血与继发性青光眼:IV. 兔眼房水内红细胞体外及体内镰变的速率和百分比
Ophthalmic Surg. 1979 Apr;10(4):62-9.
9
Ethnobotanical survey and cytotoxicity testing of plants of South-western Nigeria used to treat cancer, with isolation of cytotoxic constituents from Cajanus cajan Millsp. leaves.尼日利亚西南部用于治疗癌症的植物的民族植物学调查和细胞毒性测试,从兵豆叶片中分离出具有细胞毒性的成分。
J Ethnopharmacol. 2010 Mar 24;128(2):501-12. doi: 10.1016/j.jep.2010.01.009. Epub 2010 Jan 11.
10
Anti-sickling potential of a Nigerian herbal formula (ajawaron HF) and the major plant component (Cissus populnea L. CPK).一种尼日利亚草药配方(阿贾瓦龙HF)及主要植物成分(柔毛白粉藤CPK)的抗镰状化潜力
Phytother Res. 2003 Dec;17(10):1173-6. doi: 10.1002/ptr.1323.

引用本文的文献

1
"We Cure Sickle Cell Disease with Herbs": Perspectives of Herbal Medicine Practitioners Treating Sickle Cell Disease in the Acholi Sub-Region.“我们用草药治愈镰状细胞病”:阿乔利次区域治疗镰状细胞病的草药医生的观点
J Multidiscip Healthc. 2025 Jul 28;18:4267-4277. doi: 10.2147/JMDH.S534707. eCollection 2025.
2
In vitro study of anti-sickling effects of aqueous extracts of Garcinia kola (seeds), Zingiber officinale (rhizomes) and Allium sativum(bulbs) on sodium metabisulphite-treated HBSS erythrocytes.可乐果(种子)、姜(根茎)和大蒜(鳞茎)水提取物对偏亚硫酸氢钠处理的HBSS红细胞抗镰变作用的体外研究。
BMC Complement Med Ther. 2025 Jul 4;25(1):241. doi: 10.1186/s12906-025-04943-6.
3
The Dietary Use of Pigeon Pea for Human and Animal Diets.
食用鸽豆作为人类和动物的饮食。
ScientificWorldJournal. 2022 Jan 24;2022:4873008. doi: 10.1155/2022/4873008. eCollection 2022.
4
Potential of Three Ethnomedicinal Plants as Antisickling Agents.三种民族药用植物作为抗镰状化剂的潜力。
Mol Pharm. 2017 Jan 3;14(1):172-182. doi: 10.1021/acs.molpharmaceut.6b00767. Epub 2016 Dec 5.