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《槐米对镰状细胞的逆转作用》。

The Reversion of Sickled Cells by Cajanus cajan.

机构信息

Department of Biochemistry, University of Port Harcourt, P.M.B. 5323 Port Harcourt, Nigeria.

出版信息

Planta Med. 1985 Dec;51(6):504-7. doi: 10.1055/s-2007-969576.

Abstract

Boiled and crude ethanolic extracts of edible CAJANUS CAJAN beans were prepared and used for IN VITRO studies involving 14 individual blood samples obtained from confirmed sickle cell (HbSS) patients. It was demonstrated that the extracts were able not only to inhibit sickling in sodium metabisulphite solution, but also quickly reverted to normal morphology, already sickled erythrocytes. There was also a noticeable improvement in the general morphology of the sickle cell erythrocytes after coming into contact with the plant extracts.

摘要

食用腰果的水煮和粗提乙醇提取物被制备并用于涉及从确诊镰状细胞(HbSS)患者中获得的 14 份个体血液样本的体外研究。结果表明,这些提取物不仅能够抑制亚硫酸钠溶液中的镰状化,而且还能够迅速将已经镰状化的红细胞恢复正常形态。与植物提取物接触后,镰状细胞的一般形态也有明显改善。

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