Aujesky Drahomir, Long Judith A, Fine Michael J, Ibrahim Said A
Division of Internal Medicine, the Clinical Epidemiology Center, University of Lausanne, Lausanne, Switzerland.
J Clin Epidemiol. 2007 Apr;60(4):410-6. doi: 10.1016/j.jclinepi.2006.06.023. Epub 2006 Dec 27.
Limited data exist on the quality of care for patients with venous thromboembolism (VTE), and it is unknown whether the processes and outcomes of care for this illness differ between African Americans and whites.
We retrospectively studied 168 patients hospitalized for VTE in two Veterans Affairs hospitals during fiscal years 2000-2002. Patient characteristics, information about processes of care, and medical outcomes at 90 days after the index VTE event were abstracted from medical records. We used logistic regression to explore associations between race, processes of care, and the overall 90-day complication rate (i.e., death, bleeding, or recurrent VTE), adjusting for patient baseline characteristics.
Multivariable analysis demonstrated that administration of warfarin within 1 day of starting heparin (odds ratio [OR] 0.20, 95% confidence interval [CI]: 0.05-0.42) and overlap of heparin and warfarin treatment >or=4 days (OR 0.09, 95% CI: 0.02-0.50) were associated with a lower complication rate, and African American race was associated with a higher complication rate (OR 5.2, 95% CI: 1.3-21.6). Race was not significantly associated with the performance of processes of care in multivariable analysis.
Although African Americans had an increased risk of complications following VTE, race was not independently associated with the use of processes of care for VTE.
关于静脉血栓栓塞症(VTE)患者护理质量的数据有限,且尚不清楚非裔美国人和白人在这种疾病的护理过程和结果上是否存在差异。
我们回顾性研究了2000 - 2002财政年度在两家退伍军人事务医院因VTE住院的168例患者。从病历中提取患者特征、护理过程信息以及首次VTE事件后90天的医疗结果。我们使用逻辑回归来探讨种族、护理过程与总体90天并发症发生率(即死亡、出血或复发性VTE)之间的关联,并对患者基线特征进行调整。
多变量分析表明,在开始使用肝素后1天内给予华法林(比值比[OR]0.20,95%置信区间[CI]:0.05 - 0.42)以及肝素和华法林治疗重叠≥4天(OR 0.09,95% CI:0.02 - 0.50)与较低的并发症发生率相关,而非裔美国人种族与较高的并发症发生率相关(OR 5.2,95% CI:1.3 - 21.6)。在多变量分析中,种族与护理过程的执行情况无显著关联。
尽管非裔美国人在VTE后发生并发症的风险增加,但种族与VTE护理过程的使用并无独立关联。