Kahveci Arzu, Seyahi Nurhan, Seyahi Emire, Altiparmak Mehmet R, Ataman Rezzan, Serdengecti Kamil
Division of Nephrology, Department of Internal Medicine, Cerrahpasa Medical Faculty, Istanbul University, Istanbul - Turkey.
J Nephrol. 2007 Jan-Feb;20(1):103-6.
We report the case of a young male patient with nephrotic syndrome and multiple venous thromboses. The patient presented various aggregated thrombophilic risk factors. He was found to be homozygous for factor V Leiden mutation and his anticardiolipin antibody and homocysteine levels were high. The association between nephrotic syndrome and venous thrombosis is well known. However the presence of disseminated thrombosis should prompt an intensive work-up for the detection of thrombotic risk factors and aggressive anticoagulant therapy.
我们报告了一例患有肾病综合征和多处静脉血栓形成的年轻男性患者。该患者存在多种聚集性血栓形成倾向危险因素。发现他为凝血因子V莱顿突变纯合子，其抗心磷脂抗体和同型半胱氨酸水平较高。肾病综合征与静脉血栓形成之间的关联是众所周知的。然而，弥散性血栓形成的存在应促使进行全面检查以检测血栓形成危险因素，并进行积极的抗凝治疗。
