Shukuya Takehito, Hirano Satoshi, Takeda Yuichiro, Ito Hideyuki, Hurihata Kaneyuki, Sugiyama Haruhito, Kobayashi Nobuyuki, Kudo Koichiro
Department of Respiratory Medicine, International Medical Center of Japan.
Nihon Kokyuki Gakkai Zasshi. 2007 Feb;45(2):174-9.
A 61-year-old man visited another hospital with chief complaints of dry cough, appetite loss and body weight loss. On chest X ray film and CT, right supraclavicular and mediastinal lymph nodes were swollen. For further examination, he was referred to our hospital and diagnosed as primary mediastinal choriocarcinoma. We conducted surgery after four cycles of chemotherapy using cisplatin, etoposide and bleomycin. After chemotherapy, residual tumors were found on chest CT. In FDG-PET some parts of the residual tumors seen on CT showed much less uptake and the others showed similar uptake. Histologically the areas showing similar uptake contained more viable cells, and the other areas showing less uptake almost completely consisted of necrotic tissue. We believe FDG-PET can be useful to evaluate the viability of tumors after chemotherapy in extra gonadal choriocarcinoma in the mediastinum.
一名61岁男性因干咳、食欲减退和体重减轻为主诉就诊于另一家医院。胸部X线片和CT显示右锁骨上及纵隔淋巴结肿大。为进一步检查,他被转诊至我院,诊断为原发性纵隔绒毛膜癌。我们使用顺铂、依托泊苷和博来霉素进行了四个周期化疗后进行了手术。化疗后,胸部CT发现残留肿瘤。在FDG-PET检查中,CT上显示的残留肿瘤部分摄取明显减少,而其他部分摄取相似。组织学检查显示,摄取相似的区域含有更多存活细胞,而摄取减少的其他区域几乎完全由坏死组织组成。我们认为FDG-PET可用于评估纵隔性腺外绒毛膜癌化疗后肿瘤的存活情况。