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[Involvement of nitric oxide in the mechanism of adrenergic responses of systemic circulation].

作者信息

Osadchiĭ L I, Balueva T V, Sergeev I V

出版信息

Izv Akad Nauk Ser Biol. 2007 Jan-Feb(1):45-50.

PMID:17352199
Abstract

Increased pressor response to the infusion of alpha1-adrenoceptor agonist phenylephrine was observed in conditions of inhibited NO synthesis: the mean blood pressure increased from 33.7 to 41.1% and the total peripheral resistance increased from 6.8 to 22.0%. The effect of vasodilation induced by NO secretion in the vascular endothelium after the stimulation by alpha1-adrenoceptors on the degree of pressor changes and changes in the total peripheral resistance is proposed.

摘要

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