Sauerwein R W, Lammers J W, Horrevorts A M
Department of Medical Microbiology, University Hospital, University of Nijmegen, The Netherlands.
Chest. 1992 Feb;101(2):555-7. doi: 10.1378/chest.101.2.555.
A patient with deteriorating pulmonary melioidosis rapidly recovered after treatment with ceftazidime. To prevent possible relapses, an oral maintenance regimen of amoxicillin and clavulanic acid was prescribed for a period of three months. Melioidosis is caused by Pseudomonas pseudomallei. It is an insidious disease because of its variable clinical presentation, possible long-term asymptomatic carriage, broad-spectrum resistance to first-line antibiotics, and high mortality rate. As in our patient, the diagnosis should be particularly considered when there is reduced immunologic resistance and previous exposure in endemic areas, such as Southeast Asia.
一名肺类鼻疽病病情恶化的患者在接受头孢他啶治疗后迅速康复。为防止可能的复发，开了阿莫西林和克拉维酸的口服维持治疗方案，为期三个月。类鼻疽病由类鼻疽假单胞菌引起。它是一种隐匿性疾病，因其临床表现多样、可能长期无症状携带、对一线抗生素具有广谱耐药性以及死亡率高。正如我们的患者一样，当免疫抵抗力下降且既往有在流行地区（如东南亚）接触史时，应特别考虑作出诊断。
