Manfrini Olivia, Slucca Michela, Bugiardini Raffaele
Dipartimento di Medicina Interna, Cardioangiologia, Epatologia, Università degli Studi Alma Mater", Bologna.
G Ital Cardiol (Rome). 2007 Jan;8(1):28-33.
Optical coherence tomography (OCT) is a recently developed technology capable of micron-scale imaging. Its high resolution (10-20 microm) makes intravascular OCT imaging the most interesting method for assessing atherosclerotic plaque microstructure in patients suffering from coronary artery disease. OCT allowed measurement of the thickness of the plaque fibrous cap, as well as identification of intima, media, and external elastic membrane in patients with normal coronary arteries. However, significant limitations still exist, including poor penetration in non-transparent tissue. The aim of this review is to give an update on OCT on the basis of the existing literature, with an overview of the strong and weak features of this technique.
光学相干断层扫描（OCT）是一种最近开发的能够进行微米级成像的技术。其高分辨率（10 - 20微米）使血管内OCT成像成为评估冠心病患者动脉粥样硬化斑块微观结构最具吸引力的方法。OCT能够测量斑块纤维帽的厚度，还能识别正常冠状动脉患者的内膜、中膜和外弹力膜。然而，仍然存在显著局限性，包括在非透明组织中的穿透性较差。本综述的目的是在现有文献的基础上对OCT进行更新，概述该技术的优缺点。
