Wu Ting, Engelhardt Martin, Fieten Lorenz, Popovic Aleksandra, Radermacher Klaus
Helmholtz Institute for Biomedical Engineering, RWTH Aachen University, Aachen, Germany.
Med Image Comput Comput Assist Interv. 2006;9(Pt 1):9-16. doi: 10.1007/11866565_2.
We present a new approach for cranial implant design which uses anatomical constrained deformation based on reference models. The methodological framework contains three steps: patient-specific generation of the reference model containing the anatomical constraints about the skull shape; determination of the spatial correspondence between the patient skull and the reference model by 3D matching; adaptive deformation of the fragment on the reference model corresponding to the defect area on the patient skull for implant design. The proposed method was validated by simulating the reconstruction of artificially generated defects on healthy skulls. The validation results show that this approach can generate implant geometry very fast and with satisfactory quality. This approach also outperforms the surface interpolation method in reconstructing cranial defects.
我们提出了一种用于颅骨植入物设计的新方法，该方法基于参考模型使用解剖学约束变形。该方法框架包含三个步骤：针对包含颅骨形状解剖学约束的参考模型进行患者特异性生成；通过三维匹配确定患者颅骨与参考模型之间的空间对应关系；针对患者颅骨上的缺损区域，对参考模型上的碎片进行自适应变形以进行植入物设计。通过模拟健康颅骨上人工生成的缺损的重建对所提出的方法进行了验证。验证结果表明，这种方法能够非常快速地生成质量令人满意的植入物几何形状。在重建颅骨缺损方面，这种方法也优于表面插值法。
