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急诊酒精戒断治疗的变异性和结局差异。

Treatment variability and outcome differences in the emergency department management of alcohol withdrawal.

机构信息

Addiction Medicine Service, St. Joseph's Health Centre, Toronto, Ontario, Canada.

出版信息

CJEM. 2005 Mar;7(2):87-92. doi: 10.1017/s1481803500013038.

Abstract

OBJECTIVE

Evidence suggests that symptom-triggered benzodiazepine treatment for patients with alcohol withdrawal reduces complication rates and emergency department lengths of stay. Our objective was to describe the management of alcohol withdrawal in 2 urban emergency departments.

METHODS

A structured chart audit was performed for patients with alcohol-related problems who presented to 2 Toronto hospitals over a 2-year period.

RESULTS

A total of 209 emergency department charts were audited. Patient characteristics were similar in both hospitals. None of the patients had been assessed using the Clinical Institute Withdrawal Assessment for Alcohol (CIWA-Ar) scale. Patients at one hospital received substantially higher mean diazepam doses (64 mg v. 26 mg; p < 0.001) than did the patients at the other hospital, and the patients at the first hospital had fewer seizures during their emergency department stay (1% v. 9%; p = 0.012). Patients spent an average of 9 hours and 40 minutes in the emergency department.

CONCLUSION

There is significant variability in the documentation and treatment of alcohol withdrawal. Lower benzodiazepine doses are associated with higher rate of withdrawal seizures and prolonged emergency department length of stay. A standardized approach using symptom-triggered management is likely to improve outcomes for patients presenting with alcohol withdrawal.

摘要

目的

有证据表明,针对酒精戒断患者采用症状触发式苯二氮䓬类药物治疗可降低并发症发生率和急诊停留时间。我们的目的是描述 2 家市级急诊部对酒精戒断的处理方法。

方法

对 2 年间在多伦多 2 家医院就诊的与酒精相关问题的患者进行了结构化图表审查。

结果

共审查了 209 份急诊病历。2 家医院的患者特征相似。均未使用临床戒断评估酒精量表(CIWA-Ar)对患者进行评估。一家医院的患者接受的地西泮平均剂量明显更高(64mg 比 26mg;p<0.001),且该院患者在急诊停留期间癫痫发作的发生率更低(1%比 9%;p=0.012)。患者平均在急诊停留 9 小时 40 分钟。

结论

酒精戒断的记录和治疗存在显著差异。较低的苯二氮䓬类药物剂量与更高的戒断性癫痫发作率和更长的急诊停留时间相关。采用症状触发式管理的标准化方法可能会改善酒精戒断患者的预后。

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