de Goederen-van der Meij Suzan, Pierik Robert G J M, Oudkerk Pool Marco, Gouma Dirk J, Mathus-Vliegen Lisbeth M
Department of Surgery, Academic Medical Centre, Amsterdam, The Netherlands.
Obes Surg. 2007 Jan;17(1):88-94. doi: 10.1007/s11695-007-9011-8.
We studied whether weight loss by intragastric balloon would predict the outcome of subsequent gastric banding with regard to weight loss and BMI reduction.
A prospective cohort of patients with a body mass index (BMI)>40 kg/m(2) received an intragastric balloon for 6 months followed by laparoscopic adjustable gastric banding (LAGB). Successful balloon-induced weight loss was defined as > or =10% weight loss after 6 months. Successful surgical weight loss was defined as an additional 15% weight loss in the following 12 months. Patients were divided in group A, losing > or =10% of their initial weight with 6 months' balloon treatment, and group B, losing <10% of their initial weight.
In 40 patients (32 female, 8 male; age 36.6 yr, range 26-54), the mean BMI decreased from 46.5 to 40.5 kg/m(2) (P<0.001) after 6 months of balloon treatment and to 35.2 kg/m(2) (P<0.001) 12 months after LAGB. Group A (25 patients) and group B (15 patients) had a significant difference in BMI decrease, 12.4 vs 9.0 kg/m(2) (P<0.05), after the total study duration of 18 months. However, there was no difference in BMI reduction (4.7 kg/m(2) vs 5.8 kg/m(2)) in the 12 months after LAGB. 6 patients in group A lost > or =10% of their starting weight during 6 months balloon treatment as well as > or =15% 12 months following LAGB. 6 patients in group B lost <10% of their starting weight after 6 months of BIB, but also lost > or =15% 12 months following LAGB.
Intragastric balloon did not predict the success of subsequent LAGB.
我们研究了胃内球囊减重是否能预测后续胃束带术在减重和降低体重指数（BMI）方面的效果。
对一组体重指数（BMI）>40 kg/m² 的患者进行前瞻性队列研究，先接受胃内球囊治疗6个月，随后进行腹腔镜可调节胃束带术（LAGB）。球囊诱导的成功减重定义为6个月后体重减轻≥10%。手术成功减重定义为在接下来的12个月内体重额外减轻15%。患者被分为A组，在6个月的球囊治疗中体重减轻≥10%；B组，体重减轻<10%。
40例患者（32例女性，8例男性；年龄36.6岁，范围26 - 54岁），球囊治疗6个月后，平均BMI从46.5降至40.5 kg/m²（P<0.001），LAGB术后12个月降至35.2 kg/m²（P<0.001）。在18个月的总研究期后，A组（25例患者）和B组（15例患者）在BMI降低方面有显著差异，分别为12.4 vs 9.0 kg/m²（P<0.05）。然而，LAGB术后12个月，两组在BMI降低方面无差异（4.7 kg/m² vs 5.8 kg/m²）。A组有6例患者在6个月的球囊治疗期间体重减轻≥10%，且LAGB术后12个月体重减轻≥15%。B组有6例患者在6个月的BIB治疗后体重减轻<10%，但LAGB术后12个月体重减轻也≥15%。
胃内球囊不能预测后续LAGB的成功与否。
