van den Berg Henk, Caron Hubert N
Department of Pediatric Oncology, Emma Children Hospital AMC, University of Amsterdam, Amsterdam, The Netherlands.
J Pediatr Hematol Oncol. 2007 Mar;29(3):187-9. doi: 10.1097/MPH.0b013e318033506a.
Paratesticular lesions of neuroblastoma are in contrast to testicular infiltration extremely rare. Six cases were reported in literature. It is debated, whether localizations are either metastatic lesions or part of multicentric disease. We present a 9-month-old boy with stage 4 neuroblastoma, in which an unsuspected scrotal localization was already present at birth. This lesion had not grown, in contrast to the other sites. The case illustrates that neuroblastoma is a multicentric tumor, originating in the adrenal area and paratesticular sympathic remnants. The lesions differed in clinical behavior. It further illustrates that multicentric localizations exhibit different clinical behavior.
与睾丸浸润相比，睾丸旁神经母细胞瘤极为罕见。文献中报道了6例。关于这些病变是转移性病灶还是多中心疾病的一部分存在争议。我们报告了一名9个月大患有4期神经母细胞瘤的男孩，其出生时就存在一个未被怀疑的阴囊病灶。与其他部位的病灶不同，这个病灶没有生长。该病例表明神经母细胞瘤是一种多中心肿瘤，起源于肾上腺区域和睾丸旁交感神经残余。这些病灶在临床行为上有所不同。它进一步表明多中心病灶表现出不同的临床行为。
