全乙酰化对γ-环糊精构象的影响。

Effect of peracetylation on the conformation of gamma-cyclodextrin.

作者信息

Caira Mino R, Bettinetti Giampiero, Sorrenti Milena, Catenacci Laura, Cruickshank Dyanne, Davies Kate

机构信息

Department of Chemistry, University of Cape Town, Rondebosch, 7701, South Africa.

出版信息

Chem Commun (Camb). 2007 Mar 28(12):1221-3. doi: 10.1039/b616681d. Epub 2007 Jan 10.

DOI:10.1039/b616681d

PMID:17356762

Abstract

The well-known, fourfold symmetry of the gamma-CD molecule in its solid inclusion complexes is lost on peracetylation, which yields a highly distorted host molecule in which self-inclusion of acetyl residues divides the macrocyclic cavity into two distinct sub-cavities that accommodate solvent molecules.

摘要

γ-环糊精分子在其固体包合物中众所周知的四重对称性在全乙酰化时丧失，这产生了一种高度扭曲的主体分子，其中乙酰基的自包合将大环腔分成两个容纳溶剂分子的不同子腔。