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早期内镜括约肌切开术与早期腹腔镜胆囊切除术治疗重症急性胆源性胰腺炎——初步报告

Early endoscopic sphincterotomy and early laparoscopic cholecystectomy in the treatment of severe acute biliary pancreatitis--a preliminary report.

作者信息

Panek J, Karcz D, Rembiasz K, Budzyński A, Zasada J

机构信息

2nd Chair of General Surgery, Jagiellonian University, Collegium Medicum, Kraków, Poland.

出版信息

Adv Med Sci. 2006;51:103-4.

Abstract

PURPOSE

The proper timing of endoscopic sphincterotomy and laparoscopic cholecystectomy in acute biliary pancreatitis is still a subject of controversies. The following rapid report presents preliminary data concerning treatment of patients with severe form of necrotizing biliary pancreatitis (SNBP) with the sequence of minimal invasive procedures (endoscopic sphincterotomy and laparoscopic cholecystectomy) performed in the first 48 hours after admission.

MATERIAL AND METHODS

Twelve patients with SNBP were included in the study. The described above procedures were performed in all of the patients within 48 hours. We evaluated clinical outcome, complications, time of stay in hospital and also some morphological (white blood cells) and liver parameters (AST, ALT, bilirubin, ALP and GGT) of these patients in the course of the disease.

RESULTS

Two patients died. Two other ones has local complications. We did not observe major complications after ERCP with ES and after laparoscopic cholecystectomy. Additionally, the lavage of the abdominal cavity was performed and drainage was established during laparoscopic cholecystectomy. Conversion in our group occurred in 1 person. Later complications in the course of the disease were caused by the its progression and not related to the performed procedures.

CONCLUSIONS

The results are very incurable, however, performing these types of procedures in the experienced centers deserves to be taken into account.

摘要

目的

内镜括约肌切开术和腹腔镜胆囊切除术在急性胆源性胰腺炎中的恰当时机仍是一个有争议的话题。以下快速报告展示了关于在入院后48小时内按顺序进行微创操作(内镜括约肌切开术和腹腔镜胆囊切除术)治疗重症坏死性胆源性胰腺炎(SNBP)患者的初步数据。

材料与方法

12例SNBP患者纳入研究。上述操作在所有患者入院48小时内进行。我们评估了这些患者在疾病过程中的临床结局、并发症、住院时间以及一些形态学指标(白细胞)和肝脏指标(谷草转氨酶、谷丙转氨酶、胆红素、碱性磷酸酶和γ-谷氨酰转肽酶)。

结果

2例患者死亡。另外2例出现局部并发症。我们未观察到内镜逆行胰胆管造影术联合内镜括约肌切开术及腹腔镜胆囊切除术后出现严重并发症。此外,在腹腔镜胆囊切除术期间进行了腹腔灌洗并建立了引流。我们组有1例中转手术。疾病过程中的后期并发症是由疾病进展引起的,与所进行的操作无关。

结论

结果不容乐观,然而,在经验丰富的中心开展这类手术值得考虑。

引用本文的文献

1
Turkish Society of Gastroenterology: Pancreas Working Group, Acute Pancreatitis Committee Consensus Report.
Turk J Gastroenterol. 2024 Nov 11;35(Suppl 1):S1-S44. doi: 10.5152/tjg.2024.24392.

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