Gutierrez Maria Fernanda, Matiz Adriana, Trespalacios Alba Alicia, Parra Miguel, Riaño Marcela, Mercado Marcela
Department of Microbiology, School of Science, Universidad Javeriana, Carrera edificio Felix Restrepo Of 313, Bogotá, Colombia.
Rev Latinoam Microbiol. 2006 Jan-Mar;48(1):17-23.
Infectious acute diarrhea (IAD) is an important health problem affecting a large number of Latin-American children. Several reports show that bacteria, parasites and virus are involved in the burden of this disease. Most reports reveal Rotavirus A as the responsible etiological agent, at the same time, there seems to be some correlation between IAD and seasonal weather changes. To learn about the type of microbial agents associated with IAD in children during mildly changing yearly climatic conditions, as found in a high altitude tropical city, and to identify the viral agents affecting this population, stool samples from 300 children under 5 years of age were studied throughout a one-year period. Bacteria and intestinal parasites were identified by routine methods, while viruses were detected and typed by EIA and PCR. 20.6% of the IAD studied was associated with bacteria; 9% with parasites and 40% with virus. Group C Rotavirus accounted for 20.2%, group A Rotavirus for 13% and Calicivirus 10%. During November-April (p < 0.007) more virus associated IAD was found, while bacteria (p < 0.03) or parasite (p < 0.00014) related IAD was prevalent from May to October. The mild seasonal weather changes don't seem to be associated with any other microbial agent.
感染性急性腹泻（IAD）是一个影响大量拉丁美洲儿童的重要健康问题。多项报告显示，细菌、寄生虫和病毒与该疾病的负担有关。大多数报告表明A组轮状病毒是主要病原体，与此同时，IAD与季节性气候变化之间似乎存在一定关联。为了解在高海拔热带城市中每年气候温和变化期间与儿童IAD相关的微生物种类，并确定影响该人群的病毒病原体，我们在一年时间里对300名5岁以下儿童的粪便样本进行了研究。通过常规方法鉴定细菌和肠道寄生虫，同时通过酶免疫分析（EIA）和聚合酶链反应（PCR）检测并分型病毒。在研究的IAD病例中，20.6%与细菌有关；9%与寄生虫有关，40%与病毒有关。C组轮状病毒占20.2%，A组轮状病毒占13%，杯状病毒占10%。在11月至4月期间（p < 0.007），发现更多与病毒相关的IAD病例，而与细菌（p < 0.03）或寄生虫（p < 0.00014）相关的IAD病例在5月至10月更为普遍。温和的季节性气候变化似乎与任何其他微生物病原体均无关联。
