Modrzyński Marek, Zawisza Edward, Mazurek Henryk
Poradnia Alergologiczna NZOZ Euromedica w Grudziadzu.
Otolaryngol Pol. 2006;60(6):865-71.
The adenoidectomy is the most often made operation in small children but the reasons of adenoid hypertrophy are not completely explain. Some researches show that in part of children allergy can be a risk factor for adenoid hypertrophy. The main aim of this study was the analysis of adenoid hypertrophy in children with different allergic diseases.
Two separate groups of children were examined. The study group consisted of 436 children between 4 and 9 years old with allergic rhinitis and/or bronchial asthma and/or atopic dermatitis hypersensitive to house dust mites (interview, positive skin-prick test results). The control group consisted of 229 non-atopic children (negative interview and skin-prick tests) in the similar age. In the both groups we examined the incidence of adenoid hypertrophy and its dependence of the kind of allergic disease, age, sex, infections, results of skin-prick test and other sensitisation.
The probability of adenoid hypertrophy was statistically more significant (logistic regression analysis) only in children from the study group with allergic rhinitis. There were no differences in adenoid hypertrophy incidence between children with other allergic diseases and the control group. The children from the study group with adenoid hypertrophy were more often hypersensitive to pollen and moulds allergens than the children without adenoid hypertrophy (chi square test). But there were no differences in the incidence of infection, age, sex and results of skin-prick tests.
The result of our study suggests that the chance of adenoid hypertrophy in allergic children hypersensitive to dust mites is greater only in them with allergic rhinitis.
腺样体切除术是小儿最常施行的手术，但腺样体肥大的原因尚未完全明确。一些研究表明，在部分儿童中，过敏可能是腺样体肥大的一个危险因素。本研究的主要目的是分析患有不同过敏性疾病儿童的腺样体肥大情况。
对两组不同的儿童进行了检查。研究组由436名4至9岁的儿童组成，他们患有过敏性鼻炎和/或支气管哮喘和/或对屋尘螨过敏的特应性皮炎（通过访谈、皮肤点刺试验阳性结果确诊）。对照组由229名年龄相仿的非特应性儿童组成（访谈和皮肤点刺试验均为阴性）。在两组中，我们检查了腺样体肥大的发生率及其与过敏性疾病类型、年龄、性别、感染、皮肤点刺试验结果及其他致敏情况的相关性。
仅在患有过敏性鼻炎的研究组儿童中，腺样体肥大的概率在统计学上更显著（逻辑回归分析）。患有其他过敏性疾病的儿童与对照组在腺样体肥大发生率上没有差异。与没有腺样体肥大的儿童相比，研究组中患有腺样体肥大的儿童对花粉和霉菌过敏原过敏的情况更常见（卡方检验）。但在感染发生率、年龄、性别和皮肤点刺试验结果方面没有差异。
我们的研究结果表明，对尘螨过敏的过敏性儿童中，仅患有过敏性鼻炎的儿童发生腺样体肥大的几率更高。
