Newmark Jonathan, Langer Janice M, Capacio Benedict, Barr John, McIntosh Roger G
U.S. Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, MD 21010, USA.
Mil Med. 2007 Feb;172(2):196-8. doi: 10.7205/milmed.172.2.196.
A 35-year-old active duty service member sustained a 6.5% body surface area burn as a result of exposure to the chemical warfare agent sulfur mustard, which is the most severe mustard exposure of a U.S. military member since World War II that is known to us. New techniques were used to demonstrate the detectable persistence of mustard metabolites in the patient's blood for at least 41 days after exposure, validating these techniques for the first time for a human mustard patient; they were also used for the first time with human mustard blister fluid. The techniques extend eightfold the period of time that mustard exposure can be definitively diagnosed, compared with previous techniques. Although this patient's lesions were never life-threatening, he required 2 weeks of intensive burn care. He has been left with ongoing posttraumatic stress disorder and has had an incomplete dermatological recovery. In a major terrorist attack involving many patients exposed to sulfur mustard, care resources would be depleted quickly.
一名35岁的现役军人因接触化学战剂硫芥而遭受了6.5%体表面积的烧伤，这是自第二次世界大战以来已知的美国军人遭受的最严重的芥子气暴露。采用新技术证明，芥子气代谢产物在患者血液中至少在暴露后41天内可检测到，这首次验证了这些技术可用于人类芥子气患者；这些技术还首次用于人类芥子气水疱液。与以前的技术相比，这些技术将芥子气暴露可明确诊断的时间延长了八倍。尽管该患者的损伤从未危及生命，但他需要2周的强化烧伤护理。他一直患有创伤后应激障碍，皮肤恢复不完全。在一次涉及许多接触硫芥患者的重大恐怖袭击中，护理资源将很快耗尽。
