Bar A, Kafri Y, Mukamel D
Department of Physics of Complex Systems, Weizmann Institute of Science, Rehovot, Israel 76100.
Phys Rev Lett. 2007 Jan 19;98(3):038103. doi: 10.1103/PhysRevLett.98.038103. Epub 2007 Jan 17.
The dynamics of a loop in DNA molecules at the denaturation transition is studied by scaling arguments and numerical simulations. The autocorrelation function of the state of complementary bases (either closed or open) is calculated. The long-time decay of the autocorrelation function is expressed in terms of the loop exponent c both for homopolymers and heteropolymers. This suggests an experimental method for measuring the exponent c using florescence correlation spectroscopy.
通过标度论证和数值模拟研究了DNA分子在变性转变时环的动力学。计算了互补碱基状态(闭合或开放)的自相关函数。对于均聚物和杂聚物,自相关函数的长时间衰减都用环指数c来表示。这提出了一种使用荧光相关光谱法测量指数c的实验方法。