Kanma K, Saito Y, Nagamoto N, Sagawa M, Sato M, Takahashi S, Usuda K, Endo C, Nakada T, Ota S
Department of Surgery, Research Institute for Chest Disease and Cancer, Tohoku University.
Kyobu Geka. 1992 Jan;45(1):75-9.
Out of 201 patients with roentogenographically occult bronchogenic squamous cell carcinoma, 165 lesions underwent surgical operations, while 41 lesions underwent non-invasive therapy. The 5-year survival rate including all causes of death, was significantly higher in the surgical operation group than that in the non-invasive therapy group (83% vs 43%). Among 14 cases who received Nd-YAG laser treatment, one case died but 4 cases are alive bearing cancer. Since time span of follow-up period is short, it is hard to say that the prognosis of the Nd-YAG laser therapy in fair. Nd-YAG laser treatments were effective for cancers which did not invade beyond bronchial cartilage. From the bronchoscopic examinations and studies with resected lungs, we suggest that Nd-YAG laser treatments may be effective when cancer is extended within 10 mm wide and has only a slight findings in bronchoscopy.
在201例X线检查隐匿的支气管源性鳞状细胞癌患者中,165个病灶接受了外科手术,41个病灶接受了非侵入性治疗。包括各种死因在内的5年生存率,手术治疗组显著高于非侵入性治疗组(83%对43%)。在接受钕钇铝石榴石激光治疗的14例患者中,1例死亡,但4例仍带癌存活。由于随访时间跨度较短,很难说钕钇铝石榴石激光治疗的预后良好。钕钇铝石榴石激光治疗对未侵犯支气管软骨以外的癌症有效。通过支气管镜检查和对切除肺的研究,我们认为当癌灶扩展宽度在10毫米以内且支气管镜检查仅有轻微表现时,钕钇铝石榴石激光治疗可能有效。