Quea G, Romero K, Garcia-Velasco J A
Instituto Valenciano de Infertilidad IVI-Madrid, Rey Juan Carlos University, Madrid, Spain.
Reprod Biomed Online. 2007 Mar;14(3):375-83. doi: 10.1016/s1472-6483(10)60882-6.
Multiple pregnancies are a serious adverse event of IVF treatment. Several strategies have been developed to improve embryo selection and embryo developmental potential to increase pregnancy rates without increasing the risk of multiple pregnancies. The only way to effectively solve this problem is to reduce the number of embryos transferred to one. The introduction of extended embryo culture has provided IVF programmes with a valuable tool to select more accurately those embryos with a higher implantation potential. The concept of single embryo transfer presents a clinical dilemma with seemingly opposing sides: one seeking to maintain acceptable pregnancy rates and the other seeking to reduce the number of twin births or high order multiple pregnancies. The present review addresses the potential benefits and drawbacks of blastocyst transfer.
多胎妊娠是体外受精治疗的一种严重不良事件。已经开发了几种策略来改善胚胎选择和胚胎发育潜能，以提高妊娠率而不增加多胎妊娠的风险。有效解决这个问题的唯一方法是将移植的胚胎数量减少到一个。延长胚胎培养的引入为体外受精方案提供了一种有价值的工具，以便更准确地选择那些具有较高着床潜能的胚胎。单胚胎移植的概念带来了一个看似矛盾的临床困境：一方试图维持可接受的妊娠率，另一方则试图减少双胎或多胎妊娠的数量。本综述探讨了囊胚移植的潜在益处和缺点。
