Chae Younbyoung, Park Hi-Joon, Hahm Dae-Hyun, Hong Meesuk, Ha Eunyoung, Park Hun-Kuk, Lee Hyejung
Acupuncture and Meridian Science Research Center, Kyung Hee University, Seoul 130-701, Korea.
Neurol Res. 2007;29 Suppl 1:S42-8. doi: 10.1179/016164107X172284.
Since the late 1990s, imaging studies have allowed the visualization of brain response to acupuncture stimulation with alteration in blood flow. In 1998, the first functional magnetic resonance imaging (fMRI) study for the Korean acupuncture was published and thereafter, many subsequent neuroimaging studies with acupuncture have been published and revealed that acupuncture modulates central nervous system in human being. The purpose of this review is to summarize and evaluate the acupuncture studies using fMRI.
A survey of computerized literature searches for experimental studies of acupuncture studies using fMRI revealed that a total of 19 studies were published from 1998 to 2005.
These studies have mainly focused on the correlation between acupoints and corresponding brain cortices, acupoint-specific patterns of brain activity. The analgesic effect of acupuncture implied that the pain network, including the hypothalamus and limbic system, was induced by different kinds of acupuncture stimulation. There are still several limitations in these experimental designs.
We reviewed studies that contributed to an understanding of the neurophysiologic mechanisms of acupuncture with the hope that this review will be of benefit to the future traditional Korean acupunctural fMRI studies.
自20世纪90年代末以来,影像学研究已能够可视化大脑对针刺刺激的反应以及血流变化。1998年,首篇关于韩国针刺的功能磁共振成像(fMRI)研究发表,此后,许多关于针刺的后续神经影像学研究相继发表,并揭示针刺可调节人体中枢神经系统。本综述的目的是总结和评估使用fMRI的针刺研究。
对利用fMRI进行针刺研究的实验性研究的计算机文献检索调查显示,1998年至2005年共发表了19项研究。
这些研究主要集中在穴位与相应大脑皮层之间的相关性、穴位特异性脑活动模式。针刺的镇痛作用表明,包括下丘脑和边缘系统在内的疼痛网络是由不同类型的针刺刺激诱发的。这些实验设计仍存在一些局限性。
我们回顾了有助于理解针刺神经生理机制的研究,希望本综述对未来韩国传统针刺fMRI研究有所帮助。