Zhou Xiang, Zhou Jie, Zhang Fan, Shu Qi, Wu Yan, Chang Hui-Min, Zhang Bin, Cai Rong-Lin, Yu Qing
College of Acupuncture and Moxibustion, Anhui University of Chinese Medicine, Hefei, 230038, Anhui Province, China.
Anhui Wannan Rehabilitation Hospital (The Fifth People's Hospital of Wuhu), Wuhu, 241000, Anhui Province, China.
Heliyon. 2024 Sep 20;10(19):e38197. doi: 10.1016/j.heliyon.2024.e38197. eCollection 2024 Oct 15.
Cardiovascular disease is the leading cause of death worldwide. As a traditional Chinese treatment method, acupuncture has a unique role in restoring the balance of the human body environment. Due to its safety, non-invasive nature, and effectiveness in treating cardiovascular diseases, acupuncture has been widely welcomed and recognized among the world. A large amount of evidence shows that acupuncture can effectively regulate cardiovascular diseases through the autonomic nervous system. The hypothalamus, as an important component of regulating the autonomic nervous system, plays an important role in regulating the internal environment, maintaining homeostasis, and preserving physiological balance. However, there is currently a scarcity of review articles on acupuncture signal transduction and acupuncture improving cardiovascular disease through the hypothalamus and autonomic nervous system.
This review delves into the transduction of acupuncture signals and their neural regulatory mechanisms on the hypothalamus and autonomic nervous system, elucidating their impact on cardiovascular disease.
Review the basic and clinical studies on acupuncture signal transduction mechanisms and the role of the hypothalamus and ANS in acupuncture treatment of cardiovascular diseases published in four English databases (PubMed, Web of Science, MEDLINE, and Springer Cochrane Library) and two Chinese databases (Wanfang Database and China National Knowledge Infrastructure Database) over the past 20 years.
Through sensory stimulation, acupuncture effectively transmits signals from the periphery to the hypothalamus, where they are integrated, and finally regulate the autonomic nervous system to treat cardiovascular diseases.
Acupuncture exhibits significant potential as a therapeutic modality for cardiovascular diseases by orchestrating autonomic nervous system regulation via the hypothalamus, thereby gifting novel perspectives and methodologies for the prevention and treatment of cardiovascular ailments.
心血管疾病是全球主要的死亡原因。作为一种中医疗法，针灸在恢复人体环境平衡方面具有独特作用。由于其安全性、非侵入性以及在治疗心血管疾病方面的有效性，针灸在世界范围内受到广泛欢迎和认可。大量证据表明，针灸可通过自主神经系统有效调节心血管疾病。下丘脑作为调节自主神经系统的重要组成部分，在调节内环境、维持体内平衡和保持生理平衡方面发挥着重要作用。然而，目前关于针灸信号转导以及针灸通过下丘脑和自主神经系统改善心血管疾病的综述文章较为匮乏。
本综述深入探讨针灸信号的转导及其对下丘脑和自主神经系统的神经调节机制，阐明其对心血管疾病的影响。
回顾过去20年在四个英文数据库（PubMed、Web of Science、MEDLINE和Springer Cochrane Library）和两个中文数据库（万方数据库和中国知网数据库）中发表的关于针灸信号转导机制以及下丘脑和自主神经系统在针灸治疗心血管疾病中作用的基础和临床研究。
通过感觉刺激，针灸有效地将信号从外周传递到下丘脑，在下丘脑进行整合，最终调节自主神经系统以治疗心血管疾病。
针灸通过下丘脑协调自主神经系统调节，在心血管疾病治疗方面展现出巨大潜力，为心血管疾病的预防和治疗提供了新的视角和方法。
