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肺部病变的射频消融术。

Radiofrequency ablation of pulmonary lesions.

作者信息

Cariati M, Giordano G, Midulla M, Calati A M, Sacrini A, Raveglia F, Cornalba G P

机构信息

U.O. Radiologia Diagnostica Interventistica, Azienda Ospedaliera San Paolo, and Scuola di Scpecializzazione in Radiodiagnostica, Università di Milano, Italy.

出版信息

Radiol Med. 2007 Mar;112(2):149-56. doi: 10.1007/s11547-007-0131-y. Epub 2007 Mar 19.

Abstract

PURPOSE

Radiofrequency ablation uses the thermal energy produced by a generator to create a coagulative necrosis. The method is well established for the treatment of a variety of primary and secondary cancers of the liver but is less well studied for the treatment of lung malignancies.

MATERIALS AND METHODS

From March 2005 to March 2006, 11 patients (seven men and four women) with single or multiple pulmonary nodules underwent radiofrequency ablation of 12 unresectable pulmonary tumours. Follow-up computed tomography (CT) was performed at 1, 3, 6, and 12 months after radiofrequency ablation. Lesions were evaluated for dimensions and contrast enhancement.

RESULTS

Radiofrequency ablation was well tolerated by all patients. Postprocedural complications included four cases of pneumothorax treated with simple aspiration without tube placement and one case of small parenchymal haemorrhage. There were no major complications.

CONCLUSIONS

Radiofrequency ablation of primary or secondary pulmonary lesions is a safe and technically feasible option for the management of unresectable pulmonary malignancies.

摘要

目的

射频消融利用发生器产生的热能造成凝固性坏死。该方法在治疗多种原发性和继发性肝癌方面已得到充分确立,但在治疗肺恶性肿瘤方面的研究较少。

材料与方法

2005年3月至2006年3月,11例(7例男性和4例女性)有单个或多个肺结节的患者接受了12个不可切除肺肿瘤的射频消融治疗。在射频消融后1、3、6和12个月进行随访计算机断层扫描(CT)。评估病变的大小和对比增强情况。

结果

所有患者对射频消融耐受性良好。术后并发症包括4例气胸,经单纯抽吸治疗,未放置胸腔引流管,1例小的实质内出血。无重大并发症。

结论

对原发性或继发性肺部病变进行射频消融是治疗不可切除肺恶性肿瘤的一种安全且技术上可行的选择。

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