下颌下腺小细胞癌：一种罕见的小圆形蓝细胞肿瘤。

Small cell carcinoma of the submandibular gland: a rare small round blue cell tumor.

作者信息

Walters David M, Little Stewart C, Hessler Richard B, Gourin Christine G

机构信息

Department of Otolaryngology-Head and Neck Surgery, Medical College of Georgia, Augusta, GA 30912, USA.

出版信息

Am J Otolaryngol. 2007 Mar-Apr;28(2):118-21. doi: 10.1016/j.amjoto.2006.06.013.

DOI:10.1016/j.amjoto.2006.06.013

PMID:17362818

Abstract

The presence of small cell carcinoma within the submandibular gland is an uncommon clinical entity. However, other small round blue cell tumors are encountered in the head and neck with greater frequency. These include lymphoma, Ewing's sarcoma, melanoma, esthesioneuroblastoma, and neuroblastoma. A basic knowledge of the immunohistochemical studies available to distinguish each these tumors from one another significantly improves the frequency of accurate and timely initial diagnosis. We report a case of small cell carcinoma of the submandibular gland and review the other common small round blue cell tumors that occur within the head and neck. We utilize an acronym, LEMONS, to organize our review and facilitate improved retention of the differential diagnosis for small round blue cell tumors of the head and neck.

摘要

下颌下腺内出现小细胞癌是一种罕见的临床情况。然而，头颈部更常遇到其他小圆形蓝细胞肿瘤。这些包括淋巴瘤、尤因肉瘤、黑色素瘤、嗅神经母细胞瘤和神经母细胞瘤。了解可用于区分这些肿瘤的免疫组织化学研究的基本知识，可显著提高准确及时进行初步诊断的频率。我们报告一例下颌下腺小细胞癌病例，并回顾头颈部发生的其他常见小圆形蓝细胞肿瘤。我们使用首字母缩写词LEMONS来组织我们的综述，并便于更好地记住头颈部小圆形蓝细胞肿瘤的鉴别诊断。