二尖瓣脱垂与突发性耳聋。
Mitral valve prolapse and sudden deafness.
作者信息
Vazquez R, Solanellas J, Alfageme I, Valenzuela-García L F, Pavon R, Leal J, Fernandez A J, Sanchez-Burguillos F J
出版信息
Int J Cardiol. 2008 Mar 14;124(3):370-1. doi: 10.1016/j.ijcard.2006.11.240. Epub 2007 Mar 23.
To examine the association between MVP and Idiopathic Sudden Sensorineural Hearing loss (ISSNHL). 349 subjects, 86 with ISSNHL and 263 controls underwent a 2D-echocardiography. Patients with ISSNHL had higher rates of MVP (29.1% vs 2.7%, p<0.001), mitral leaflet thickening (15.1% vs 2.3%, p<0.001), mitral regurgitation (16.3% vs 6.5%, p=0.02) and left atrial enlargement (11.6% vs 3.8%, p=0.01). Our results support the hypothesis that MVP could be one of the etiological factors of ISSNHL.
为研究二尖瓣脱垂（MVP）与特发性突发性感音神经性听力损失（ISSNHL）之间的关联。349名受试者，其中86名患有ISSNHL，263名作为对照，均接受了二维超声心动图检查。ISSNHL患者的MVP发生率更高（29.1% 对2.7%，p<0.001）、二尖瓣叶增厚发生率更高（15.1% 对2.3%，p<0.001）、二尖瓣反流发生率更高（16.3% 对6.5%，p=0.02）以及左心房扩大发生率更高（11.6% 对3.8%，p=0.01）。我们的结果支持MVP可能是ISSNHL病因之一的假说。
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