Men-Chi H, Ravigururajan T S
Department of Mechanical Engineering, Wichita State University, Wichita, KS 67260-0133, USA.
Cardiovasc Eng. 2007 Mar;7(1):7-16. doi: 10.1007/s10558-007-9026-8.
Atherosclerosis is a leading cause of heart diseases and mortality around the world. Recently, cryoplasty has emerged as a potential alternative method to treat arterial atherosclerosis. Finite element heat transfer and mass transfer models are developed using ANSYS in this study. The model analyzes the heat transfer within the atherosclerotic plaque and arterial wall during the cryoplasty procedure. The model is useful in predicting the transient temperature through the diseased wall tissues. The results may be used to decide required treatment procedure to effectively freeze the plaque with minimal damage to the healthy arterial tissues. Finally, the model investigates the parameters that may effect temperature distribution within the tissues during the ablative procedure.
动脉粥样硬化是全球心脏病和死亡率的主要原因。最近，冷冻球囊血管成形术已成为治疗动脉粥样硬化的一种潜在替代方法。本研究使用ANSYS开发了有限元传热和传质模型。该模型分析了冷冻球囊血管成形术过程中动脉粥样硬化斑块和动脉壁内的热传递。该模型有助于预测病变壁组织中的瞬态温度。结果可用于确定所需的治疗程序，以便在对健康动脉组织造成最小损伤的情况下有效冷冻斑块。最后，该模型研究了在消融过程中可能影响组织内温度分布的参数。
