高钙尿性肾结石患者血清1,25-二羟维生素D水平与肠道钙吸收分数率之间的相关性。磷酸盐的作用。
Correlation between 1.25 dihydroxyvitamin D serum levels and fractional rate of intestinal calcium absorption in hypercalciuric nephrolithiasis. Role of phosphate.
作者信息
Alvarez-Arroyo M V, Traba M L, Rapado A, de la Piedra C, Torralbo M
机构信息
Laboratorio de la Unidad Metabólica, Fundación Jiménez Diaz, Spain.
出版信息
Urol Res. 1992;20(1):96-7. doi: 10.1007/BF00294348.
PMID:1736497
Abstract
Different mechanisms could explain the elevated calcium elimination, the main cause of calcium oxalate renal stones. Our results suggest that phosphate levels are decreased in patients with absorptive hypercalciuric nephrolithiasis and elevated serum dihydroxyvitamin D. This could be the reason why in this group of patients oral phosphate treatment prevented hypercalciuria and renal lithiasis.
摘要
不同的机制可以解释钙排泄增加这一草酸钙肾结石的主要成因。我们的研究结果表明，在吸收性高钙尿性肾结石且血清二羟基维生素D升高的患者中，磷酸盐水平降低。这可能就是为什么在这组患者中，口服磷酸盐治疗可预防高钙尿症和肾结石。
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