Chopde C T, Brahmankar D M, Jadhav S S, Hardas A P, Dorle A K
Indian J Physiol Pharmacol. 1975 Jul-Sep;19(3):146-51.
Lauric, Myristic and Palmitic acids had no appreciable effect whereas Stearic, Oleic and Linoleic acids caused some reduction in dog blood pressure. Pressor responses to epinephrine and nor-epinephrine were potentiated whereas the depressor response to isoproterenol was reduced during the infusion of fatty acids in dogs. ACTH alone, which causes mobilization of free fatty acids had no appreciable effect on blood pressure responses to catecholamines, however, its administration followed by salicylate produced marked potentiation of the pressor responses to epinephrine and nor-epinephrine; the depressor response to isoproterenol was reduced.
月桂酸、肉豆蔻酸和棕榈酸没有明显作用，而硬脂酸、油酸和亚油酸会使犬血压有所降低。在给犬输注脂肪酸期间，对肾上腺素和去甲肾上腺素的升压反应增强，而对异丙肾上腺素的降压反应减弱。单独使用促肾上腺皮质激素（ACTH）可促使游离脂肪酸动员，对儿茶酚胺的血压反应没有明显影响，然而，在使用ACTH后再给予水杨酸盐，会使对肾上腺素和去甲肾上腺素的升压反应显著增强；对异丙肾上腺素的降压反应减弱。
