Bedeschi Emanuela, Campari Cinzia, Candela Silvia, Collini Giorgia, Caranci Nicola, Frasca Gabriella, Galassi Claudia, Francesca Gabriella, Vigotti Maria Angela
Dipartimento di Sanità Pubblica-ASL di Reggio Emilia, Reggio Emilia, Italy.
J Toxicol Environ Health A. 2007 Feb 1;70(3-4):261-5. doi: 10.1080/15287390600884784.
Short-term effects of air pollution on daily mortality and hospital admissions for respiratory causes are well documented. Few studies, however, explore the association between exposure to air pollution and daily emergency room visits for respiratory disorders, particularly in Italy and particularly among children as a susceptible population. A time-series analysis was conducted to explore the short-term association between air pollutants (PM10, total suspended particulates [TSP], NO2, SO2, CO, O3) and pediatric emergency room (ER) visits in a small city of northern Italy, Reggio Emilia, during the period 03/01/2001-03/31/2002. There were 1051 ER visits included in the study. Data were analyzed using generalized additive models (GAM), adjusting for various confounding variables, including temperature, humidity, and pollens (Graminaceae). The analyses were also stratified according to the nationality of children (Italians and foreigners). In single-pollutant models, the strongest associations were observed at lag 3 for a 10-microg/m3 increase of TSP (2.7% increase in ER, 95% CI 0.7-4.6) and PM10 (3.0% increase, 95% CI 0.4-5.7), and at lag 4 for a 10-microg/m3 increase of NO2 (11.0% increase in ER, 95% CI 3.6-18.8). At lag 3, the percentage increase in ER visits is similar for the 2 groups of children (Italians and foreigners) for TSP and PM10. The results of the study support the findings that air pollution is a relevant determinant of deterioration of respiratory health among children.
空气污染对每日死亡率及呼吸道疾病住院率的短期影响已有充分记录。然而,很少有研究探讨空气污染暴露与因呼吸道疾病导致的每日急诊就诊之间的关联,尤其是在意大利,特别是针对作为易感人群的儿童。进行了一项时间序列分析,以探究2001年1月3日至2002年3月31日期间,意大利北部小城雷焦艾米利亚空气中的污染物(PM10、总悬浮颗粒物[TSP]、NO2、SO2、CO、O3)与儿科急诊就诊之间的短期关联。该研究纳入了1051次急诊就诊数据。使用广义相加模型(GAM)对数据进行分析,并对包括温度、湿度和花粉(禾本科)在内的各种混杂变量进行了校正。分析还根据儿童的国籍(意大利人和外国人)进行了分层。在单污染物模型中,对于TSP每增加10微克/立方米,在滞后3天时观察到最强的关联(急诊就诊增加2.7%,95%置信区间0.7 - 4.6)以及PM10(增加3.0%,95%置信区间0.4 - 5.7);对于NO2每增加10微克/立方米,在滞后4天时观察到最强的关联(急诊就诊增加11.0%,95%置信区间3.6 - 18.8)。在滞后3天时,两组儿童(意大利人和外国人)因TSP和PM10导致的急诊就诊增加百分比相似。该研究结果支持了空气污染是儿童呼吸道健康恶化的一个相关决定因素这一发现。