Tsilimbaris Miltiadis K, Gotzaridis Stratos, Charisis Spyridon K, Kymionis Georgios, Christodoulakis Emmanouil V
University Eye Clinic, University of Crete Medical School, Greece.
Semin Ophthalmol. 2007 Jan-Mar;22(1):39-42. doi: 10.1080/08820530601182576.
To report a small, retrospective, noncomparative case series (3 patients) of idiopathic macular holes with spontaneous closure in previously vitrectomized eyes.
The first patient developed a macular hole 14 months after vitrectomy for penetrating ocular trauma. In the rest of the patients, the macular holes were documented ten days and two months after vitrectomies for retinal detachment.
In all cases the macular holes resolved spontaneously 2 years, 6 and 9 months after their documentation, respectively.
Despite the limitations placed by the small sample of studied patients, it seems that spontaneous closure of macular holes developed after vitrectomy can happen as part of their natural course. Both pathogenetic and repair factors involved in macular hole can act spontaneously in a vitrectomized eye.
报告一组小型回顾性非对照病例系列(3例患者),这些患者为既往接受过玻璃体切割术的眼发生特发性黄斑裂孔且自发闭合。
首例患者在因穿透性眼外伤行玻璃体切割术后14个月出现黄斑裂孔。其余患者在因视网膜脱离行玻璃体切割术后10天和2个月记录到黄斑裂孔。
在所有病例中,黄斑裂孔分别在记录后的2年、6个月和9个月自发闭合。
尽管研究患者样本量小存在局限性,但玻璃体切割术后发生的黄斑裂孔似乎可作为其自然病程的一部分而自发闭合。黄斑裂孔所涉及的发病机制和修复因素在接受玻璃体切割术的眼中均可自发发挥作用。