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德克萨斯州休斯顿一个大型“超级避难所”内居住的卡特里娜飓风撤离者中诺如病毒胃肠炎的广泛爆发:预防经验教训

Widespread outbreak of norovirus gastroenteritis among evacuees of Hurricane Katrina residing in a large "megashelter" in Houston, Texas: lessons learned for prevention.

作者信息

Yee Eileen L, Palacio Herminia, Atmar Robert L, Shah Umair, Kilborn Cindy, Faul Mark, Gavagan Thomas E, Feigin Ralph D, Versalovic James, Neill Frederick H, Panlilio Adelisa L, Miller Mark, Spahr James, Glass Roger I

机构信息

Centers for Disease Control and Prevention, Coordinating Center for Infectious Diseases, Div. of Viral Diseases, Atlanta, GA 30333, USA.

出版信息

Clin Infect Dis. 2007 Apr 15;44(8):1032-9. doi: 10.1086/512195. Epub 2007 Mar 2.

Abstract

BACKGROUND

After Hurricane Katrina, an estimated 200,000 persons were evacuated to the Houston metropolitan area, >27,000 of whom were housed in 1 large "megashelter," the Reliant Park Complex. We investigated an outbreak of gastroenteritis reported among the evacuees who resided in the Reliant Park Complex to assess the spread of the infectious agent, norovirus, and to implement and evaluate the effectiveness of interventions used for control.

METHODS

Public health authorities conducted surveillance of gastroenteritis among evacuees treated at the Reliant Park Medical Clinic during 2-12 September 2005. Basic demographic and clinical data were recorded. Specimens of stool and vomitus were collected and tested for bacteria, parasites, and viruses. Shelter census data were used to estimate the daily incidence of disease.

RESULTS

During a period of 11 days, >1000 patients were treated at the clinic for gastroenteritis, which accounted for 17% of all clinic visits. Norovirus was the sole enteric pathogen identified, but multiple different strains were involved. Among the evacuees residing in the Reliant Park Complex, the incidence of gastroenteritis was estimated to be 4.6 visits per 1000 persons per day, and among the evacuees who resided there for 9 days, 1 (4%) of 24 persons would have been ill. Intensive public health measures were promptly instituted but did not definitively slow the progression of the outbreak of norovirus gastroenteritis.

CONCLUSIONS

Our investigation underscores the difficulties in managing such outbreaks in crowded settings and the need for rapid, sensitive laboratory assays to detect norovirus. Additional research is needed to establish more effective measures to control and prevent this highly contagious gastrointestinal illness.

摘要

背景

卡特里娜飓风过后,估计有20万人被疏散到休斯敦大都市区,其中超过2.7万人被安置在一个大型“超级避难所”——赖安特公园综合设施内。我们对居住在赖安特公园综合设施的撤离人员中报告的胃肠炎疫情进行了调查,以评估传染性病原体诺如病毒的传播情况,并实施和评估用于控制疫情的干预措施的有效性。

方法

公共卫生当局对2005年9月2日至12日在赖安特公园医疗诊所接受治疗的撤离人员中的胃肠炎情况进行了监测。记录了基本的人口统计学和临床数据。收集了粪便和呕吐物样本,检测其中的细菌、寄生虫和病毒。利用避难所人口普查数据估算疾病的每日发病率。

结果

在11天的时间里,超过1000名患者因胃肠炎在该诊所接受治疗,占诊所所有就诊人数的17%。诺如病毒是唯一被鉴定出的肠道病原体,但涉及多种不同毒株。在居住在赖安特公园综合设施的撤离人员中,胃肠炎发病率估计为每1000人每天4.6人次就诊,而在居住9天的撤离人员中,24人中有1人(4%)患病。迅速采取了强化公共卫生措施,但未能最终减缓诺如病毒胃肠炎疫情的蔓延。

结论

我们的调查凸显了在拥挤环境中管理此类疫情的困难,以及需要快速、灵敏的实验室检测方法来检测诺如病毒。需要进一步开展研究,以确立更有效的措施来控制和预防这种高度传染性的胃肠道疾病。

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