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Reactome: a knowledge base of biologic pathways and processes.

作者信息

Vastrik Imre, D'Eustachio Peter, Schmidt Esther, Gopinath Gopal, Croft David, de Bono Bernard, Gillespie Marc, Jassal Bijay, Lewis Suzanna, Matthews Lisa, Wu Guanming, Birney Ewan, Stein Lincoln

机构信息

European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK.

出版信息

Genome Biol. 2007;8(3):R39. doi: 10.1186/gb-2007-8-3-r39.


DOI:10.1186/gb-2007-8-3-r39
PMID:17367534
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1868929/
Abstract

Reactome http://www.reactome.org, an online curated resource for human pathway data, provides infrastructure for computation across the biologic reaction network. We use Reactome to infer equivalent reactions in multiple nonhuman species, and present data on the reliability of these inferred reactions for the distantly related eukaryote Saccharomyces cerevisiae. Finally, we describe the use of Reactome both as a learning resource and as a computational tool to aid in the interpretation of microarrays and similar large-scale datasets.

摘要

相似文献

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本文引用的文献

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