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人类生物途径和过程的Reactome知识库。

Reactome knowledgebase of human biological pathways and processes.

作者信息

D'Eustachio Peter

机构信息

Department of Biochemistry, New York University School of Medicine, New York, NY, USA.

出版信息

Methods Mol Biol. 2011;694:49-61. doi: 10.1007/978-1-60761-977-2_4.

Abstract

The Reactome Knowledgebase is an online, manually curated resource that provides an integrated view of the molecular details of human biological processes that range from metabolism to DNA replication and repair to signaling cascades. Its data model allows these diverse processes to be represented in a consistent way to facilitate usage as online text and as a resource for data mining, modeling, and analysis of large-scale expression data sets over the full range of human biological processes.

摘要

Reactome知识库是一个在线的、经过人工整理的资源,它提供了从新陈代谢到DNA复制与修复再到信号级联反应等人类生物过程分子细节的综合视图。其数据模型允许以一致的方式呈现这些不同的过程,以便于作为在线文本使用,并作为在全范围人类生物过程中进行数据挖掘、建模和大规模表达数据集分析的资源。

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