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一名慢性淋巴细胞白血病患者肺部曲菌球后继发鼻眶及肺部接合菌病

Rhinoorbital and pulmonary zygomycosis post pulmonary aspergilloma in a patient with chronic lymphocytic leukaemia.

作者信息

Barr Andrew, Nolan Marianne, Grant William, Costello Christine, Petrou Michael A

机构信息

Department of Haematology, Chelsea and Westminster Hospital, London, UK.

出版信息

Acta Biomed. 2006;77 Suppl 4:13-8.

Abstract

A patient with an 18-year history of chronic lymphocytic leukaemia developed zygomycosis of the orbit, sinuses and nasal bones together with pulmonary fungal nodes due to Absidia corymbifera while on high dose steroids and four months after successful treatment of pulmonary aspergilloma with liposomal amphotericin B followed by oral voriconazole. He was treated successfully with extensive surgical debridement, intravenous liposomal amphotericin B and intravenous itraconazole.

摘要

一名有18年慢性淋巴细胞白血病病史的患者,在接受高剂量类固醇治疗期间,以及在用脂质体两性霉素B成功治疗肺曲菌球并随后口服伏立康唑四个月后,发生了由伞枝犁头霉引起的眼眶、鼻窦和鼻骨接合菌病以及肺部真菌结节。通过广泛的手术清创、静脉注射脂质体两性霉素B和静脉注射伊曲康唑,他得到了成功治疗。

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