Phipps A R, Godfrey A M, Durrant K R, Millard P R
Department of Plastic Surgery, Radcliffe Infirmary, Oxford.
Br J Plast Surg. 1992 Jan;45(1):30-3. doi: 10.1016/0007-1226(92)90111-a.
A historical series of patients with primary cutaneous malignant melanoma is reviewed. These patients had been treated with a single therapeutic dose of irradiation to the tumour and surrounding skin immediately before surgical excision. Some patients had also received a single necrotising dose of radiotherapy to the tumour itself. Recurrence and survival rates have been examined retrospectively in the light of reviewed histology, and compared with other published series. Preoperative radiotherapy was found to have no significant influence on the outcome of surgical treatment of primary malignant melanoma.
回顾了一组原发性皮肤恶性黑色素瘤患者的病史。这些患者在手术切除前，曾对肿瘤及周围皮肤进行单次治疗剂量的照射。部分患者还对肿瘤本身进行了单次坏死剂量的放疗。根据回顾的组织学情况对复发率和生存率进行了回顾性研究，并与其他已发表的系列进行了比较。结果发现，术前放疗对原发性恶性黑色素瘤的手术治疗结果没有显著影响。
