Dikensoy E, Balat O, Ugur M G, Ozkur A, Erkilic S
Department of Obstetrics and Gynecology, Gaziantep University, Gaziantep, Turkey.
Eur J Gynaecol Oncol. 2007;28(1):45-7.
To determine whether serum CA-125 levels, in addition to tumor size and ultrasonographic findings can help in differentiating benign ovarian cysts from malignant disease.
All postmenopausal women who had undergone explorative laporatomy for a preoperative diagnosis of an adnexal cyst between January 1999 and February 2006 were included if serum CA-125 levels were below 50 IU/ml.
Ninety-three patients with ovarian cysts and serum CA-125 levels lower than 50 IU/ml were included. Seventy-five (80%) of the patients (53 unilocular, 22 multilocular) had ovarian cysts < 13 cm. Of 18 patients with ovarian cysts > 13 cm, seven had unilocular and 11 had multilocular cysts. All the patients (n = 77) with a serum CA-125 level < 35 IU/ml had benign histopathology regardless of the tumor size or ultrasonic features. Among 16 patients with CA-125 levels between 35 and 50 IU/ml, two with unilocular cysts > 13 cm and nine with multilocular cysts (3 < 13 cm, 6 > 13 cm) had borderline histopathology.
We concluded that when unilocular ovarian cyst size is < 13 cm and serum CA-125 levels are below 35 IU/ml in a postmenopausal woman, the possibility of a benign etiology is most likely.
确定血清CA - 125水平，除肿瘤大小和超声检查结果外，是否有助于鉴别良性卵巢囊肿与恶性疾病。
纳入1999年1月至2006年2月间因术前诊断附件囊肿而接受探查性剖腹手术的所有绝经后妇女，前提是血清CA - 125水平低于50 IU/ml。
纳入93例卵巢囊肿且血清CA - 125水平低于50 IU/ml的患者。75例（80%）患者（53例单房，22例多房）卵巢囊肿< 13 cm。18例卵巢囊肿> 13 cm的患者中，7例为单房囊肿，11例为多房囊肿。所有血清CA - 125水平< 35 IU/ml的患者（n = 77），无论肿瘤大小或超声特征如何，组织病理学均为良性。在16例CA - 125水平在35至50 IU/ml之间的患者中，2例单房囊肿> 13 cm的患者和9例多房囊肿患者（3例< 13 cm，6例> > cm）组织病理学为交界性。
我们得出结论，绝经后妇女单房卵巢囊肿大小< 13 cm且血清CA - 125水平低于35 IU/ml时，病因最可能为良性。
