Buster John E, Krotz Stephan
Division of Reproductive Endocrinology and Infertility, Baylor College of Medicine, Houston, Texas 77030, USA.
Semin Reprod Med. 2007 Mar;25(2):131-3. doi: 10.1055/s-2007-970052.
Reproductive performance may be an important variable in treatment selection for unruptured ectopic pregnancy. The impact of treatment choice on reproductive performance is not known. We searched the literature and then tabulated published case reports on laparoscopic salpingostomy, multiple-dose methotrexate, single-dose methotrexate, and expectant management. From this analysis, we are unable to conclude any clinically detectable differences in the efficacy of these four most common treatments for unruptured ectopic pregnancy. Even more recent reports using life tables are inconclusive because the studies are not randomized. We conclude that concern for long-term reproductive performance should not be a factor in selecting between any of these four commonly used treatments for unruptured ectopic pregnancy.
生殖性能可能是未破裂异位妊娠治疗选择中的一个重要变量。治疗选择对生殖性能的影响尚不清楚。我们检索了文献，然后将已发表的关于腹腔镜输卵管造口术、多剂量甲氨蝶呤、单剂量甲氨蝶呤和期待治疗的病例报告制成表格。通过该分析，我们无法得出这四种最常见的未破裂异位妊娠治疗方法在疗效上有任何临床可检测到的差异。即使是最近使用生命表的报告也没有定论，因为这些研究并非随机进行。我们得出结论，对于长期生殖性能的担忧不应成为在这四种常用的未破裂异位妊娠治疗方法中进行选择的一个因素。
