Rodgers Jo Ellen, Stough Wendy Gattis
School of Pharmacy, University of North Carolina, Chapel Hill, North Carolina 27599, USA.
Pharmacotherapy. 2007 Apr;27(4 Pt 2):18S-28S. doi: 10.1592/phco.27.4part2.18S.
Utilization of evidence-based therapy in the heart failure population includes implementation of heart failure treatment guidelines, interventions to improve prescribing, and inclusion of pharmacists on the multidisciplinary team. Use of treatment guidelines eases the challenge of selecting the appropriate drug and dosage; quality interventions by pharmacists can ensure optimal prescribing of therapy; and provision of care by a multidisciplinary team can improve outcomes in patients with heart failure. Evidence-based therapy, however, remains underutilized in the heart failure population. Barriers to utilization include misperceptions that various heart failure subpopulations do not need certain medical therapies, a fear of polypharmacy, inappropriate assumptions about adverse effects and contraindications, and cost. In fact, optimal prescribing of evidence-based therapy can actually reduce costs. Clearly documented processes and systems are needed to ensure that evidence-based therapy and education are available to every patient.
在心力衰竭患者群体中采用循证治疗包括实施心力衰竭治疗指南、改善处方开具的干预措施以及让药剂师加入多学科团队。使用治疗指南有助于应对选择合适药物和剂量的挑战;药剂师的高质量干预可确保治疗的最佳处方开具;多学科团队提供的护理可改善心力衰竭患者的治疗效果。然而,循证治疗在心力衰竭患者群体中的应用仍然不足。应用的障碍包括误解各种心力衰竭亚群不需要某些药物治疗、对多重用药的恐惧、对不良反应和禁忌症的不当假设以及成本。事实上,循证治疗的最佳处方开具实际上可以降低成本。需要有明确记录的流程和系统,以确保每位患者都能获得循证治疗和教育。