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药剂师在心力衰竭患者出院后管理中的作用:一项文献综述。

Pharmacists' role in the post-discharge management of patients with heart failure: a literature review.

作者信息

Ponniah A, Anderson B, Shakib S, Doecke C J, Angley M

机构信息

School of Pharmacy and Medical Sciences, Sansom Institute, University of South Australia, Adelaide, SA, Australia.

出版信息

J Clin Pharm Ther. 2007 Aug;32(4):343-52. doi: 10.1111/j.1365-2710.2007.00827.x.

Abstract

BACKGROUND AND OBJECTIVE

The incidence of heart failure is increasing in developed countries. In the aged population, heart failure is a common cause of hospitalization and hospital readmission, which in conjunction with post-discharge care, impose a significant cost burden. Inappropriate medication management and drug-related problems have been identified as major contributors to hospital readmissions. In order to enhance the care and clinical outcomes, and reduce treatment costs, heart failure disease management programmes (DMPs) have been developed. It is recommended that these programmes adopt a multi-disciplinary approach, and pharmacists, with their understanding and knowledge of medication management, can play a vital role in the post-discharge care of heart failure patients. The aim of this literature review was to assess the role of pharmacists in the provision of post-charge services for heart failure patients.

METHOD

An extensive literature search was undertaken to identify published studies and review articles evaluating the benefits of an enhanced medication management service for patients with heart failure post-discharge.

RESULTS

Seven studies were identified evaluating 'outpatient' or 'post-discharge' pharmacy services for patients with heart failure. In three studies, services were delivered prior to discharge with either subsequent telephone or home visit follow-up. Three studies involved the role of a pharmacist in a specialist heart failure outpatient clinic. One study focused on a home-based intervention. In six of these studies, positive outcomes, such as decreases in unplanned hospital readmissions, death rates and greater compliance and medication knowledge were demonstrated. One study did not show any difference in the number of hospitalizations between intervention and control groups. The quality of evidence of the randomized controlled trials was assessed using the Jadad scoring method. None of the studies achieved a score of more than 2, out of a maximum of 5, indicating the potential for bias.

DISCUSSION

The DMPs carried out by pharmacists have contributed to positive patient outcomes, which has highlighted the value of extending the traditional roles of pharmacists from the provision of professional guidance to the delivery of continuity of care through a more holistic and direct approach.

CONCLUSION

This review has demonstrated the effectiveness of pharmacists' interventions to reduce the morbidity and mortality associated with heart failure. However, there is an on-going need for the development and evaluation of pharmacy services for these patients.

摘要

背景与目的

在发达国家,心力衰竭的发病率正在上升。在老年人群中,心力衰竭是住院和再次住院的常见原因,这与出院后护理一起,带来了巨大的成本负担。用药管理不当和药物相关问题已被确定为再次住院的主要因素。为了加强护理和改善临床结局,并降低治疗成本,已经制定了心力衰竭疾病管理计划(DMPs)。建议这些计划采用多学科方法,而药剂师凭借其对药物管理的理解和知识,可在心力衰竭患者的出院后护理中发挥重要作用。本文献综述的目的是评估药剂师在为心力衰竭患者提供出院后服务中的作用。

方法

进行了广泛的文献检索,以确定已发表的研究和综述文章,评估为心力衰竭患者出院后提供强化药物管理服务的益处。

结果

确定了七项评估心力衰竭患者“门诊”或“出院后”药学服务的研究。在三项研究中,服务在出院前提供,随后进行电话或家访随访。三项研究涉及药剂师在心力衰竭专科门诊的作用。一项研究侧重于家庭干预。在其中六项研究中,显示出了积极的结果,如计划外再次住院率降低、死亡率降低以及依从性和用药知识提高。一项研究未显示干预组和对照组之间的住院次数有任何差异。使用Jadad评分法评估随机对照试验的证据质量。在满分5分的情况下,没有一项研究的得分超过2分,表明存在偏倚的可能性。

讨论

药剂师开展的DMPs对患者产生了积极的结果,这凸显了将药剂师的传统角色从提供专业指导扩展到通过更全面和直接的方法提供持续护理的价值。

结论

本综述证明了药剂师干预措施在降低与心力衰竭相关的发病率和死亡率方面的有效性。然而,仍需要不断开发和评估针对这些患者的药学服务。

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